Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 12/20 | 0.50 |
| ▸ | ACE | P12821 | 6/20 | 0.50 |
| ▸ | MMEL1 | Q495T6 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17164911 | 0.84 | MME (0.60) | MMEACEMMEL1 | |
| SCHEMBL18575929 | 0.84 | MME (0.60) | MMEACEMMEL1 | |
| SCHEMBL17164927 | 0.81 | MME (0.74) | MMEACEMMEL1 | |
| SCHEMBL18175793 | 0.81 | CTSS (0.46) | MMEACE | |
| SCHEMBL17169815 | 0.81 | MME (0.63) | MMEACEMMEL1 | |
| SCHEMBL17164921 | 0.79 | MME (0.62) | MMEACEMMEL1 | |
| SCHEMBL22585410 | 0.78 | MME (0.74) | MMEACEMMEL1 | |
| SCHEMBL28344119 | 0.78 | MMEL1 (0.58) | MMEACEMMEL1 | |
| SCHEMBL22585409 | 0.78 | MME (0.59) | MMEACEMMEL1 | |
| SCHEMBL21239962 | 0.75 | MME (0.65) | MMEACEMMEL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015154673-A1 | NOVEL PRODRUGS AND COMBINATIONS FOR TREATMENT OF HYPERTENSION AND CARDIOVASCULAR DISEASES | WANG ZHAOYIN (CN) | 2015-10-15 | — | — | WO | disclosed |