SCHEMBL17167390

SCHEMBL17167390

CC1(C)c2ccccc2-c2ccc(-c3ccc4c(c3)C(C)(C)c3cc(-c5cccc6c5sc5ccccc56)ccc3-4)cc21

nearest known ligand 0.56

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.56
PRKDC P78527 3/20 0.42
PARP14 Q460N5 1/20 0.40
PDK2 Q15119 10/20 0.35
MAPT P10636 1/20 0.34
PIK3CD O00329 1/20 0.33
BRD4 O60885 1/20 0.33
PIK3CA P42336 1/20 0.33
PIK3CB P42338 1/20 0.33
MTOR P42345 1/20 0.33
PIK3CG P48736 1/20 0.33
KCNH2 Q12809 1/20 0.33
BRDT Q58F21 1/20 0.33
GPR3 P46089 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30186865 0.99 ALOX5 (0.57) ALOX5PRKDCPARP14PDK2MAPT
SCHEMBL16110376 0.99 ALOX5 (0.57) ALOX5PRKDCPARP14PDK2MAPT
SCHEMBL17692347 0.97 ALOX5 (0.53) ALOX5PRKDCPARP14PDK2MAPT
SCHEMBL15893247 0.96 ALOX5 (0.51) ALOX5PRKDCPARP14PDK2MAPT
SCHEMBL14101660 0.96 ALOX5 (0.59) ALOX5PRKDCPARP14PDK2MAPT
SCHEMBL17167387 0.95 ALOX5 (0.51) ALOX5PRKDCPARP14PDK2MAPT
SCHEMBL17692378 0.95 ALOX5 (0.51) ALOX5PRKDCPARP14PDK2MAPT
SCHEMBL17692371 0.94 ALOX5 (0.50) ALOX5PRKDCPARP14PDK2MAPT
SCHEMBL18826103 0.93 ALOX5 (0.49) ALOX5PRKDCPARP14PDK2MAPT
SCHEMBL15857002 0.93 ALOX5 (0.49) ALOX5PRKDCPARP14PDK2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10038152-B2 Organic light-emitting element CANON KABUSHIKI KAISHA (JP) 2018-07-31 US disclosed
US-10038152-B2 Organic light-emitting element CANON KABUSHIKI KAISHA (JP) 2018-07-31 US disclosed
US-9899613-B2 Organic light-emitting element CANON KABUSHIKI KAISHA (JP) 2018-02-20 US disclosed
US-9899613-B2 Organic light-emitting element CANON KABUSHIKI KAISHA (JP) 2018-02-20 US disclosed
US-20150372244-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-12-24 US disclosed
US-20150372244-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-12-24 US disclosed
US-20150357586-A1 ORGANIC LIGHT-EMITTING ELEMENT SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-12-10 US disclosed
US-20150357586-A1 ORGANIC LIGHT-EMITTING ELEMENT SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-12-10 US disclosed
US-20150295188-A1 ORGANIC LIGHT-EMITTING ELEMENT SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-10-15 US disclosed
US-20150295188-A1 ORGANIC LIGHT-EMITTING ELEMENT SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-10-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10038152-B2 Organic light-emitting element NFE2L2, EML4, LEF1 ALOX5 1144/4885PRKDC 4155/4885PARP14 2044/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.