SCHEMBL17167403

SCHEMBL17167403

c1cc(-c2cccc(-c3cccc4c3sc3ccccc34)c2)cc(-c2cccc3c2oc2ccccc23)c1

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 3/20 0.52
GGPS1 O95749 1/20 0.45
PRKDC P78527 11/20 0.44
PIK3CD O00329 2/20 0.42
PIK3CB P42338 2/20 0.42
BRD4 O60885 1/20 0.42
PIK3CA P42336 1/20 0.42
MTOR P42345 1/20 0.42
PIK3CG P48736 1/20 0.42
KCNH2 Q12809 1/20 0.42
BRDT Q58F21 1/20 0.42
PTGES2 Q9H7Z7 1/20 0.42
PARP14 Q460N5 1/20 0.38
ESR2 Q92731 2/20 0.37
PRMT5 O14744 1/20 0.37
WDR77 Q9BQA1 1/20 0.37
ESR1 P03372 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15855430 1.00 ALOX5 (0.52) ALOX5GGPS1PRKDCPIK3CDPIK3CB
SCHEMBL12996614 0.97 ALOX5 (0.50) ALOX5GGPS1PRKDCPIK3CDPIK3CB
SCHEMBL14733794 0.95 ALOX5 (0.51) ALOX5GGPS1PRKDCPIK3CDPIK3CB
SCHEMBL24609432 0.94 ALOX5 (0.50) ALOX5GGPS1PRKDCPIK3CDPIK3CB
SCHEMBL24609433 0.94 ALOX5 (0.50) ALOX5GGPS1PRKDCPIK3CDPIK3CB
SCHEMBL15195409 0.94 ALOX5 (0.49) ALOX5GGPS1PRKDCPIK3CDPIK3CB
SCHEMBL12996615 0.92 ALOX5 (0.47) ALOX5GGPS1PRKDCPIK3CDPIK3CB
SCHEMBL24171892 0.92 ALOX5 (0.50) ALOX5GGPS1PRKDCPIK3CDPIK3CB
SCHEMBL19089109 0.91 ALOX5 (0.52) ALOX5GGPS1PRKDCPIK3CDPIK3CB
SCHEMBL15195407 0.91 ALOX5 (0.49) ALOX5GGPS1PRKDCPIK3CDPIK3CB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10038152-B2 Organic light-emitting element CANON KABUSHIKI KAISHA (JP) 2018-07-31 US disclosed
US-10038152-B2 Organic light-emitting element CANON KABUSHIKI KAISHA (JP) 2018-07-31 US disclosed
US-9899613-B2 Organic light-emitting element CANON KABUSHIKI KAISHA (JP) 2018-02-20 US disclosed
US-9899613-B2 Organic light-emitting element CANON KABUSHIKI KAISHA (JP) 2018-02-20 US disclosed
EP-2939289-B1 ORGANIC LIGHT-EMITTING ELEMENT CANON KK (JP) 2017-07-26 EP disclosed
US-20150372244-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-12-24 US disclosed
US-20150372244-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-12-24 US disclosed
US-20150357586-A1 ORGANIC LIGHT-EMITTING ELEMENT SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-12-10 US disclosed
US-20150357586-A1 ORGANIC LIGHT-EMITTING ELEMENT SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-12-10 US disclosed
US-20150295188-A1 ORGANIC LIGHT-EMITTING ELEMENT SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-10-15 US disclosed
US-20150295188-A1 ORGANIC LIGHT-EMITTING ELEMENT SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-10-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10038152-B2 Organic light-emitting element NFE2L2, EML4, LEF1 ALOX5 1144/4885GGPS1 2999/4885PRKDC 4155/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.