SCHEMBL17167409

SCHEMBL17167409

c1ccc(-c2cccc3c2sc2c(-c4ccc(-c5cccc6c5sc5c(-c7ccc(-c8cccc9c8sc8c(-c%10ccccc%10)cccc89)cc7)cccc56)cc4)cccc23)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LIMK1 P53667 2/20 0.56
ALOX5 P09917 1/20 0.50
MAP4K4 O95819 1/20 0.40
CSF1R P07333 1/20 0.40
FGFR1 P11362 1/20 0.40
PDGFRA P16234 1/20 0.40
LTK P29376 1/20 0.40
KDR P35968 1/20 0.40
MAPK8 P45983 1/20 0.40
CSNK1A1 P48729 1/20 0.40
CDK5 Q00535 1/20 0.40
ACVR1 Q04771 1/20 0.40
TNK2 Q07912 1/20 0.40
AURKB Q96GD4 1/20 0.40
CLK4 Q9HAZ1 1/20 0.40
DYRK1B Q9Y463 1/20 0.40
PDCD1 Q15116 1/20 0.39
CD274 Q9NZQ7 1/20 0.39
ALDH1A1 P00352 3/20 0.39
HSD17B10 Q99714 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18435734 0.98 LIMK1 (0.54) LIMK1ALOX5MAP4K4CSF1RFGFR1
SCHEMBL22151553 0.98 LIMK1 (0.54) LIMK1ALOX5MAP4K4CSF1RFGFR1
SCHEMBL14101424 0.98 LIMK1 (0.57) LIMK1ALOX5MAP4K4CSF1RFGFR1
SCHEMBL431833 0.94 LIMK1 (0.51) LIMK1ALOX5MAP4K4CSF1RFGFR1
SCHEMBL431447 0.93 LIMK1 (0.54) LIMK1ALOX5MAP4K4CSF1RFGFR1
SCHEMBL24178665 0.92 LIMK1 (0.50) LIMK1ALOX5MAP4K4CSF1RFGFR1
SCHEMBL22174858 0.92 LIMK1 (0.50) LIMK1ALOX5MAP4K4CSF1RFGFR1
SCHEMBL22174871 0.92 LIMK1 (0.50) LIMK1ALOX5MAP4K4CSF1RFGFR1
SCHEMBL22174860 0.92 LIMK1 (0.50) LIMK1ALOX5MAP4K4CSF1RFGFR1
SCHEMBL22174872 0.92 LIMK1 (0.50) LIMK1ALOX5MAP4K4CSF1RFGFR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10038152-B2 Organic light-emitting element CANON KABUSHIKI KAISHA (JP) 2018-07-31 US disclosed
US-10038152-B2 Organic light-emitting element CANON KABUSHIKI KAISHA (JP) 2018-07-31 US disclosed
US-9899613-B2 Organic light-emitting element CANON KABUSHIKI KAISHA (JP) 2018-02-20 US disclosed
US-9899613-B2 Organic light-emitting element CANON KABUSHIKI KAISHA (JP) 2018-02-20 US disclosed
EP-2939289-B1 ORGANIC LIGHT-EMITTING ELEMENT CANON KK (JP) 2017-07-26 EP disclosed
US-20150372244-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-12-24 US disclosed
US-20150372244-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-12-24 US disclosed
US-20150357586-A1 ORGANIC LIGHT-EMITTING ELEMENT SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-12-10 US disclosed
US-20150357586-A1 ORGANIC LIGHT-EMITTING ELEMENT SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-12-10 US disclosed
US-20150295188-A1 ORGANIC LIGHT-EMITTING ELEMENT SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-10-15 US disclosed
US-20150295188-A1 ORGANIC LIGHT-EMITTING ELEMENT SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-10-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10038152-B2 Organic light-emitting element NFE2L2, EML4, LEF1 LIMK1 163/4885ALOX5 1144/4885MAP4K4 2114/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.