SCHEMBL14101424

SCHEMBL14101424

c1ccc(-c2cccc3c2sc2c(-c4ccccc4)cccc23)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LIMK1 P53667 2/20 0.57
ALOX5 P09917 1/20 0.47
MAP4K4 O95819 1/20 0.41
CSF1R P07333 1/20 0.41
FGFR1 P11362 1/20 0.41
PDGFRA P16234 1/20 0.41
LTK P29376 1/20 0.41
KDR P35968 1/20 0.41
MAPK8 P45983 1/20 0.41
CSNK1A1 P48729 1/20 0.41
CDK5 Q00535 1/20 0.41
ACVR1 Q04771 1/20 0.41
TNK2 Q07912 1/20 0.41
AURKB Q96GD4 1/20 0.41
CLK4 Q9HAZ1 1/20 0.41
DYRK1B Q9Y463 1/20 0.41
ALDH1A1 P00352 3/20 0.41
HSD17B10 Q99714 2/20 0.41
HPGD P15428 1/20 0.41
BCL2L1 Q07817 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17167409 0.98 LIMK1 (0.56) LIMK1ALOX5MAP4K4CSF1RFGFR1
SCHEMBL22151553 0.96 LIMK1 (0.54) LIMK1ALOX5MAP4K4CSF1RFGFR1
SCHEMBL18435734 0.96 LIMK1 (0.54) LIMK1ALOX5MAP4K4CSF1RFGFR1
SCHEMBL431447 0.96 LIMK1 (0.54) LIMK1ALOX5MAP4K4CSF1RFGFR1
SCHEMBL16182165 0.94 LIMK1 (0.53) LIMK1ALOX5MAP4K4CSF1RFGFR1
SCHEMBL431833 0.92 LIMK1 (0.51) LIMK1ALOX5MAP4K4CSF1RFGFR1
SCHEMBL431939 0.91 LIMK1 (0.50) LIMK1ALOX5MAP4K4CSF1RFGFR1
SCHEMBL24178665 0.90 LIMK1 (0.50) LIMK1ALOX5MAP4K4CSF1RFGFR1
SCHEMBL22174872 0.90 LIMK1 (0.50) LIMK1ALOX5MAP4K4CSF1RFGFR1
SCHEMBL22174871 0.90 LIMK1 (0.50) LIMK1ALOX5MAP4K4CSF1RFGFR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3238286-B1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2024-01-17 EP disclosed
EP-3935129-B1 LIGANDS FOR NANO-SIZED MATERIALS MERCK PATENT GMBH (DE) 2023-11-29 EP disclosed
US-11832513-B2 Materials for electronic devices MERCK PATENT GMBH (DE) 2023-11-28 US disclosed
US-20230373941-A1 COMPOUNDS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-11-23 US disclosed
US-11793073-B2 Host materials for electroluminescent devices UNIVERSAL DISPLAY CORPORATION (US) 2023-10-17 US disclosed
US-20230329092-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-10-12 US disclosed
EP-4255151-A2 SPIRO[FLUORENE-9,9'-(THIO)XANTHENE] COMPOUNDS Merck Patent GmbH (DE) 2023-10-04 EP disclosed
EP-4242286-A2 MATERIALS FOR ELECTRONIC DEVICES Merck Patent GmbH (DE) 2023-09-13 EP disclosed
EP-3185333-B1 ORGANOSELENIUM MATERIALS AND THEIR USES IN ORGANIC LIGHT EMITTING DEVICES UNIVERSAL DISPLAY CORP (US) 2023-09-06 EP disclosed
EP-3714022-B1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-06-07 EP disclosed
EP-3411455-B1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2020-10-21 EP disclosed
EP-3419960-B1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2020-07-01 EP disclosed
US-20200044160-A1 ELECTRONIC DEVICE MERCK PATENT GMBH (DE) 2020-02-06 US disclosed
US-10038146-B2 Organic light-emitting compound and organic electroluminescent device using same DOOSAN CORPORATION (KR) 2018-07-31 US disclosed
US-10038146-B2 Organic light-emitting compound and organic electroluminescent device using same DOOSAN CORPORATION (KR) 2018-07-31 US disclosed
US-9837617-B2 Materials for electronic devices MERCK PATENT GMBH (DE) 2017-12-05 US disclosed
EP-3124488-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2017-02-01 EP disclosed
WO-2016131521-A1 SPIROBIFLUORENE DERIVATIVE-BASED MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2016-08-25 WO disclosed
WO-2015022051-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2015-02-19 WO disclosed
US-20080166594-A1 BENZOTHIOPHENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE MAKING USE OF THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2008-07-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11832513-B2 Materials for electronic devices PNMT, DDT, COMT LIMK1 2465/4885ALOX5 2153/4885MAP4K4 1267/4885
US-11793073-B2 Host materials for electroluminescent devices MCM6, MCM2, MCM4 LIMK1 502/4885ALOX5 3153/4885MAP4K4 3397/4885
US-10038146-B2 Organic light-emitting compound and organic electroluminescent device using same IDO1, IDO2, KYNU LIMK1 228/4885ALOX5 133/4885MAP4K4 4032/4885
US-20230373941-A1 COMPOUNDS FOR ELECTRONIC DEVICES CYP2E1, GPX1, ERCC1 LIMK1 1217/4885ALOX5 2648/4885MAP4K4 1410/4885
US-20230329092-A1 MATERIALS FOR ELECTRONIC DEVICES SOD1, GPX1, EFNA1 LIMK1 1191/4885ALOX5 3490/4885MAP4K4 1159/4885
US-20200044160-A1 ELECTRONIC DEVICE XDH, AOX1, OCIAD1 LIMK1 1054/4885ALOX5 464/4885MAP4K4 3830/4885
US-20080166594-A1 BENZOTHIOPHENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE MAKING USE OF THE SAME CYBA, BPNT1, TYR LIMK1 167/4885ALOX5 1860/4885MAP4K4 4006/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.