SCHEMBL17167478

SCHEMBL17167478

CO/C=C/c1ccc(Cl)cc1-c1cccc2c1sc1ccccc12

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP14 Q460N5 1/20 0.40
ALOX5 P09917 1/20 0.40
PRKDC P78527 5/20 0.37
PIK3CD O00329 1/20 0.35
BRD4 O60885 1/20 0.35
PIK3CA P42336 1/20 0.35
PIK3CB P42338 1/20 0.35
MTOR P42345 1/20 0.35
PIK3CG P48736 1/20 0.35
KCNH2 Q12809 1/20 0.35
BRDT Q58F21 1/20 0.35
KDM4E B2RXH2 2/20 0.35
MAPT P10636 3/20 0.34
RXFP1 Q9HBX9 2/20 0.34
TP53 P04637 1/20 0.32
THRB P10828 1/20 0.32
HTT P42858 2/20 0.32
PAX8 Q06710 1/20 0.32
MAT2A P31153 1/20 0.32
F10 P00742 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19961740 0.86 PARP14 (0.46) PARP14ALOX5PRKDCPIK3CDBRD4
SCHEMBL15856998 0.83 PARP14 (0.40) PARP14ALOX5PRKDCPIK3CDBRD4
SCHEMBL17167479 0.81 PARP14 (0.44) PARP14ALOX5PRKDCPIK3CDBRD4
SCHEMBL23759520 0.80 HDAC8 (0.46) KDM4EMAPTHTTMAT2AALDH1A1
SCHEMBL17307492 0.77 PARP14 (0.47) PARP14ALOX5PRKDCPIK3CDBRD4
SCHEMBL24473274 0.77 HDAC8 (0.41) MAPTHTTMAT2AMAPK1
SCHEMBL18767342 0.76 KDM4E (0.38) BRDTKDM4EMAPTHTTMAPK3
SCHEMBL19961729 0.74 PARP14 (0.42) PARP14ALOX5PRKDCPIK3CDBRD4
SCHEMBL18731805 0.74 ALOX5 (0.47) PARP14ALOX5PRKDCPIK3CDBRD4
SCHEMBL16745225 0.74 PARP14 (0.47) PARP14ALOX5PRKDCPIK3CDBRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230130802-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, A PLURALITY OF HOST MATERIALS, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2023-04-27 US disclosed
US-10038152-B2 Organic light-emitting element CANON KABUSHIKI KAISHA (JP) 2018-07-31 US disclosed
US-10038152-B2 Organic light-emitting element CANON KABUSHIKI KAISHA (JP) 2018-07-31 US disclosed
US-9899613-B2 Organic light-emitting element CANON KABUSHIKI KAISHA (JP) 2018-02-20 US disclosed
US-20150372244-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-12-24 US disclosed
US-20150372244-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-12-24 US disclosed
US-20150357586-A1 ORGANIC LIGHT-EMITTING ELEMENT SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-12-10 US disclosed
US-20150357586-A1 ORGANIC LIGHT-EMITTING ELEMENT SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-12-10 US disclosed
US-20150295188-A1 ORGANIC LIGHT-EMITTING ELEMENT SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-10-15 US disclosed
US-20150295188-A1 ORGANIC LIGHT-EMITTING ELEMENT SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-10-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10038152-B2 Organic light-emitting element NFE2L2, EML4, LEF1 PARP14 2044/4885ALOX5 1144/4885PRKDC 4155/4885
US-20230130802-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, A PLURALITY OF HOST MATERIALS, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME OR10J3, ELAVL1, EML4 PARP14 916/4885ALOX5 1645/4885PRKDC 1950/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.