SCHEMBL1716855

SCHEMBL1716855

CCC(CC(C)c1ccccc1)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 4/20 0.56
CYP1A2 P05177 1/20 0.47
GRM2 Q14416 1/20 0.46
GRM3 Q14832 1/20 0.46
SLC1A3 P43003 1/20 0.46
SLC1A2 P43004 1/20 0.46
SLC1A1 P43005 1/20 0.46
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
TAAR1 Q96RJ0 2/20 0.44
LMNA P02545 1/20 0.44
PPARG P37231 1/20 0.43
APAF1 O14727 1/20 0.42
CYP2D6 P10635 1/20 0.42
SRC P12931 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12228633 0.98 TRPA1 (0.54) TRPA1CYP1A2GRM2GRM3SLC1A3
SCHEMBL13418602 0.86 TRPA1 (0.50) TRPA1CYP1A2GRM2GRM3MEN1
SCHEMBL14033301 0.86 TRPA1 (0.53) TRPA1GRM2GRM3MEN1KMT2A
SCHEMBL16804936 0.86 ESR1 (0.46) TRPA1CYP1A2SLC1A3SLC1A2SLC1A1
SCHEMBL14383427 0.84 HPGD (0.43) TRPA1CYP1A2LMNAPPARGCYP2D6
SCHEMBL25129603 0.84 TAAR1 (0.48) TRPA1CYP1A2GRM2GRM3SLC1A3
SCHEMBL18290536 0.84 CPA1 (0.53) TRPA1GRM2GRM3TAAR1
SCHEMBL14501807 0.83 MEN1 (0.51) TRPA1MEN1KMT2APPARG
SCHEMBL7181326 0.81 LMNA (0.59) CYP1A2GRM2GRM3SLC1A3SLC1A2
SCHEMBL12392847 0.81 CYP1A2 (0.47) CYP1A2GRM2GRM3SLC1A3SLC1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1716159-B1 BICYCLIC SILOXANE COMPOSITIONS FOR THE RELEASE OF ACTIVE INGREDIENTS MOMENTIVE PERFORMANCE MAT INC (US) 2011-07-13 EP claimed
EP-1697386-B1 ACTIVE INGREDIENT-RELEASING CYCLIC SILOXANES GEN ELECTRIC (US) 2007-10-10 EP claimed
WO-2023088874-A1 POSITIVE TONE ULTRA THICK PHOTORESIST COMPOSITION MERCK PATENT GMBH (DE) 2023-05-25 WO disclosed
EP-2145042-B2 TEXTILE SCENTING HENKEL AG & CO KGAA (DE) 2021-10-06 EP disclosed
CN-108473484-B Compounds useful as TRPM8 modulators 弗门尼舍公司 2021-06-29 CN disclosed
EP-2145042-B1 TEXTILE SCENTING HENKEL AG & CO KGAA (DE) 2018-01-17 EP disclosed
US-20170009121-A1 COMPOSITION AND USE THEREOF, OIL-BASED DRILLING FLUID AND A METHOD FOR RAISING SHEARING FORCE OF OIL-BASED DRILLING FLUID CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2017-01-12 US disclosed
US-8574465-B2 Organic polymeric photon up-conversion nanoparticles for biological applications SONY CORPORATION (JP) 2013-11-05 US disclosed
US-20130236555-A1 ORGANIC POLYMERIC PHOTON UP-CONVERSION NANOPARTICLES FOR BIOLOGICAL APPLICATIONS SONY CORPORATION (JP) 2013-09-12 US disclosed
US-8431051-B2 Organic polymeric photon up-conversion nanoparticles for biological applications SONY CORPORATION (JP) 2013-04-30 US disclosed
US-8419985-B2 Polymeric nanoparticles comprising a medium for photon up-conversion SONY CORPORATION (JP) 2013-04-16 US disclosed
EP-1922398-A1 CONSUMER PRODUCTS HAVING VARYING ODOR PATTERNS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2008-05-21 EP disclosed
US-20070207417-A1 Photothermographic material FUJIFILM CORPORATION 2007-09-06 US disclosed
US-20070149423-A1 Spray drying TAKASAGO INTERNATIONAL CORPORATION (JP) 2007-06-28 US disclosed
US-7232652-B2 Photothermographic material and image forming method FUJIFILM CORPORATION (JP) 2007-06-19 US disclosed
EP-1767614-A1 Process for the manufacture of a spray dried powder Takasago International Corporation (JP) 2007-03-28 EP disclosed
EP-1767613-A1 Process for the manufacture of a spray dried powder Takasago International Corporation (JP) 2007-03-28 EP disclosed
WO-2007028477-A1 CONSUMER PRODUCTS HAVING VARYING ODOR PATTERNS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2007-03-15 WO disclosed
WO-2007028479-A1 CONSUMER PRODUCTS HAVING VARYING ODORS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2007-03-15 WO disclosed
US-5034429-A An unsaturated monomer, a photoinitiator and a benzene derivative for providing a cured film HITACHI CHEMICAL CO., LTD. (JP) 1991-07-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130236555-A1 ORGANIC POLYMERIC PHOTON UP-CONVERSION NANOPARTICLES FOR BIOLOGICAL APPLICATIONS UPP1, MKI67, PPOX TRPA1 292/4885CYP1A2 3112/4885GRM2 4825/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.