Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.46 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CERT1 | Q9Y5P4 | 3/20 | 0.43 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL8998277 | 0.86 | GRM2 (0.55) | LMNACYP1A2GRM2GRM3MAPK1 | |
| SCHEMBL12392847 | 0.81 | CYP1A2 (0.47) | LMNACYP1A2GRM2GRM3SLC1A3 | |
| SCHEMBL1716855 | 0.81 | TRPA1 (0.56) | LMNACYP1A2GRM2GRM3SLC1A3 | |
| SCHEMBL25129603 | 0.80 | TAAR1 (0.48) | LMNACYP1A2GRM2GRM3SLC1A3 | |
| SCHEMBL7319037 | 0.80 | CYP1A2 (0.46) | LMNACYP1A2GRM2GRM3SLC1A3 | |
| SCHEMBL12228633 | 0.80 | TRPA1 (0.54) | LMNACYP1A2GRM2GRM3SLC1A3 | |
| Propionic Acid SCHEMBL1080725 | 0.79 | LMNA (0.59) | LMNAMAPK1CERT1BCAT2KDM4E | |
| Phenylpropanol SCHEMBL27734478 | 0.78 | LMNA (0.86) | LMNAMAPK1MEN1KMT2ABCAT2 | |
| Acetic Acid SCHEMBL18759625 | 0.78 | LMNA (0.58) | LMNAMAPK1CERT1BCAT2KDM4E | |
| SCHEMBL3228613 | 0.77 | APAF1 (0.53) | LMNAMAPK1BCAT2KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1369410-A1 | Process for the stereoselective reduction of derivatives of 4-aryl-4-oxobutyric acid | BAYER AG (DE) | 2003-12-10 | — | — | EP | disclosed |