SCHEMBL17169155

SCHEMBL17169155

COc1cccc(C)c1C1=C(O)CC(C(C)CSc2ccc(C)cc2)CC1=O

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.35
HPGD P15428 4/20 0.34
LMNA P02545 2/20 0.34
CASP3 P42574 1/20 0.34
SENP8 Q96LD8 1/20 0.34
SENP7 Q9BQF6 1/20 0.34
SENP6 Q9GZR1 1/20 0.34
MAPT P10636 5/20 0.32
HSD17B10 Q99714 1/20 0.32
KDM4E B2RXH2 1/20 0.32
GPR55 Q9Y2T6 1/20 0.32
POLL Q9UGP5 1/20 0.31
ALDH1A1 P00352 1/20 0.31
POLB P06746 1/20 0.31
ALOX12 P18054 1/20 0.31
THRB P10828 1/20 0.31
ELANE P08246 2/20 0.31
GAA P10253 1/20 0.31
AADAT Q8N5Z0 1/20 0.30
TBXA2R P21731 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17169153 0.91 TBXA2R (0.35) KMT2AHPGDMAPTTBXA2R
SCHEMBL17172081 0.85 HCRTR1 (0.36) POLL
SCHEMBL15944254 0.83 KMT2A (0.36) KMT2AHPGDMAPTKDM4EALDH1A1
SCHEMBL17169162 0.82 MAPT (0.35) KMT2AHPGDMAPTPOLB
SCHEMBL17122189 0.81 TBXA2R (0.35) TBXA2R
SCHEMBL17172082 0.81 PPARD (0.36)
SCHEMBL15944250 0.79 KMT2A (0.32) KMT2AHPGD
SCHEMBL17169157 0.78 MEN1 (0.33) KMT2ALMNAMAPT
SCHEMBL17169154 0.78 MEN1 (0.31) KMT2A
SCHEMBL17122184 0.78 NR3C1 (0.31) KMT2AMAPTALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9414588-B2 Herbicide composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-08-16 US disclosed
US-20150289505-A1 HERBICIDE COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-10-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150289505-A1 HERBICIDE COMPOSITION DDT, DHFR, DERL1 KMT2A 1181/4885HPGD 585/4885LMNA 4541/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.