Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.52 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.52 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.52 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.52 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.48 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.48 |
| ▸ | CHRND | Q07001 | 3/20 | 0.48 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.48 |
| ▸ | CHRNG | P07510 | 2/20 | 0.48 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.48 |
| ▸ | GRIA1 | P42261 | 3/20 | 0.47 |
| ▸ | FAAH | O00519 | 2/20 | 0.47 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25976421 | 0.87 | PSMB5 (0.49) | CHRNB2CHRNB4CHRNA3CHRNA4CAPN1 | |
| SCHEMBL25877365 | 0.85 | CHRNB2 (0.46) | CHRNB2CHRNB4CHRNA3CHRNA4CHRND | |
| SCHEMBL25878219 | 0.85 | CHRNB2 (0.47) | CHRNB2CHRNB4CHRNA3CHRNA4CHRND | |
| SCHEMBL16485202 | 0.85 | CHRNB2 (0.56) | CHRNB2CHRNB4CHRNA3CHRNA4CHRND | |
| SCHEMBL17128773 | 0.85 | CHRNB2 (0.56) | CHRNB2CHRNB4CHRNA3CHRNA4CHRND | |
| SCHEMBL25497019 | 0.83 | FAAH (0.60) | CHRNB2CHRNB4CHRNA3CHRNA4GRIA1 | |
| SCHEMBL27377994 | 0.83 | PSMB5 (0.51) | CAPN1CAPN2FAAHPSMB5 | |
| SCHEMBL25976228 | 0.83 | CHRNB2 (0.46) | CHRNB2CHRNB4CHRNA3CHRNA4CHRND | |
| SCHEMBL17177757 | 0.81 | CHRNB2 (0.55) | CHRNB2CHRNB4CHRNA3CHRNA4CHRND | |
| SCHEMBL27433914 | 0.80 | PSMB5 (0.56) | CHRNB2CHRNB4CHRNA3CHRNA4GRIA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015155998-A1 | ANTI-HER3 ANTIBODY-DRUG CONJUGATE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2015-10-15 | — | — | WO | disclosed |