Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 17/20 | 0.40 |
| ▸ | MLYCD | O95822 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29376079 | 0.91 | GPBAR1 (0.38) | GPBAR1MLYCDALDH1A1MAPTHTT | |
| SCHEMBL16150671 | 0.91 | GPBAR1 (0.38) | GPBAR1MLYCDALDH1A1MAPTHTT | |
| SCHEMBL17482149 | 0.88 | MLYCD (0.39) | GPBAR1MLYCDSMN1; SMN2RXFP1 | |
| SCHEMBL16194524 | 0.87 | GPBAR1 (0.39) | GPBAR1MLYCD | |
| SCHEMBL17178358 | 0.87 | RXFP1 (0.38) | GPBAR1MLYCDALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL14844565 | 0.86 | GPBAR1 (0.42) | GPBAR1MLYCD | |
| SCHEMBL16151164 | 0.84 | MLYCD (0.38) | GPBAR1MLYCDALDH1A1MAPTHTT | |
| SCHEMBL29378569 | 0.84 | MLYCD (0.38) | GPBAR1MLYCDALDH1A1MAPTHTT | |
| SCHEMBL22332345 | 0.84 | GPBAR1 (0.38) | GPBAR1MLYCDALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL21574048 | 0.83 | GPBAR1 (0.36) | GPBAR1MLYCDALDH1A1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3366675-A1 | INSECTICIDAL 2-METHOXYBENZAMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-08-29 | — | — | EP | disclosed |
| EP-2763966-B1 | INSECTICIDAL 2-METHOXYBENZAMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-04-04 | — | — | EP | disclosed |
| EP-2763966-B1 | INSECTICIDAL 2-METHOXYBENZAMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-04-04 | — | — | EP | disclosed |
| US-9023873-B2 | Insecticidal 2-methoxybenzamide derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2015-05-05 | — | — | US | disclosed |
| US-9023873-B2 | Insecticidal 2-methoxybenzamide derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2015-05-05 | — | — | US | disclosed |
| US-9023873-B2 | Insecticidal 2-methoxybenzamide derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2015-05-05 | — | — | US | disclosed |
| US-20140323528-A1 | INSECTICIDAL 2-METHOXYBENZAMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2014-10-30 | — | — | US | disclosed |
| US-20140323528-A1 | INSECTICIDAL 2-METHOXYBENZAMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2014-10-30 | — | — | US | disclosed |
| US-20140323528-A1 | INSECTICIDAL 2-METHOXYBENZAMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2014-10-30 | — | — | US | disclosed |
| EP-2763966-A1 | INSECTICIDAL 2-METHOXYBENZAMIDE DERIVATIVES | Syngenta Participations AG (CH) | 2014-08-13 | — | — | EP | disclosed |
| WO-2013050261-A1 | INSECTICIDAL 2-METHOXYBENZAMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2013-04-11 | — | — | WO | disclosed |
| WO-2013050261-A1 | INSECTICIDAL 2-METHOXYBENZAMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2013-04-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140323528-A1 | INSECTICIDAL 2-METHOXYBENZAMIDE DERIVATIVES | ACHE, CDC25B, CYP1B1 | GPBAR1 1125/4885MLYCD 1137/4885ALDH1A1 236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.