SCHEMBL1718164

SCHEMBL1718164

O=c1[nH]c(=O)n(C(O)c2ccccc2)c(=O)[nH]1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DAO P14920 2/20 0.41
CYP3A4 P08684 1/20 0.39
CYP2B6 P20813 1/20 0.39
LMNA P02545 4/20 0.38
GAA P10253 2/20 0.38
ALDH1A1 P00352 2/20 0.38
HPGD P15428 2/20 0.38
MAPK1 P28482 1/20 0.38
KDM4E B2RXH2 1/20 0.38
PLA2G10 O15496 1/20 0.38
HSD17B10 Q99714 1/20 0.38
POLB P06746 2/20 0.37
APAF1 O14727 1/20 0.36
RAB9A P51151 1/20 0.36
PAX8 Q06710 1/20 0.36
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
TYMP P19971 1/20 0.35
CYP2D6 P10635 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9461365 0.80 CYP3A4 (0.41) DAOCYP3A4CYP2B6LMNAGAA
SCHEMBL11795284 0.80 GAA (0.46) DAOCYP3A4CYP2B6LMNAGAA
SCHEMBL812049 0.77 LMNA (0.44) LMNAALDH1A1MAPK1CYP2D6SRC
SCHEMBL16719672 0.67 KDM4E (0.43) CYP3A4LMNAALDH1A1MAPK1KDM4E
SCHEMBL29172397 0.66
SCHEMBL2337291 0.64 GSK3A (0.67) LMNAGAAALDH1A1HPGDMAPK1
SCHEMBL15581083 0.64 ALDH1A1 (0.47) LMNAALDH1A1MAPK1MEN1KMT2A
SCHEMBL31621004 0.63 TYMP (0.60) DAOALDH1A1HPGDRAB9AMEN1
SCHEMBL5605627 0.63
SCHEMBL11711805 0.63 GSK3A (0.64) LMNAGAAALDH1A1HPGDMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-5230143-A None JP disclosed
EP-4594398-A1 FILM COMPRISING ETHYLENE COPOLYMERS OR TERPOLYMERS, METHOD FOR MAKING IT AND ITS USE AS SOLAR CELL ENCAPSULANT Braskem S.A. (BR) 2025-08-06 EP disclosed
US-20240132681-A1 POLYETHYLENE COPOLYMERS AND TERPOLYMERS FOR TIE LAYERS AND METHODS THEREOF BRASKEM S.A. (BR) 2024-04-25 US disclosed
WO-2024069245-A1 FILM COMPRISING ETHYLENE COPOLYMERS OR TERPOLYMERS, METHOD FOR MAKING IT AND ITS USE AS SOLAR CELL ENCAPSULANT BRASKEM S.A. (BR) 2024-04-04 WO disclosed
US-8148565-B2 Method of manufacturing an organic silicon compound that contains a methacryloxy group or an acryloxy group DOW CORNING TORAY COMPANY, LTD. (JP) 2012-04-03 US disclosed
EP-1915384-B1 A METHOD OF MANUFACTURING AN ORGANIC SILICON COMPOUND THAT CONTAINS A METHACRYLOXY GROUP OR AN ACRYLOXY GROUP DOW CORNING TORAY CO LTD (JP) 2012-01-11 EP disclosed
CN-101273049-B A method of manufacturing an organic silicon compound that contains a methacryloxy group or an acryloxy group DOW CORNING TORAY CO LTD 2011-08-17 CN disclosed
US-20090306370-A1 Method Of Manufacturing An Organic Silicon Compound That Contains A Methacryloxy Group Or An Acryloxy Group DOW TORAY CO., LTD. (JP) 2009-12-10 US disclosed
CN-101273049-A A method of manufacturing an organic silicon compound that contains a methacryloxy group or an acryloxy group DOW CORNING TORAY CO LTD (JP) 2008-09-24 CN disclosed
EP-1915384-A1 A METHOD OF MANUFACTURING AN ORGANIC SILICON COMPOUND THAT CONTAINS A METHACRYLOXY GROUP OR AN ACRYLOXY GROUP Dow Corning Toray Co., Ltd. (JP) 2008-04-30 EP disclosed
WO-2007020932-A1 A METHOD OF MANUFACTURING AN ORGANIC SILICON COMPOUND THAT CONTAINS A METHACRYLOXY GROUP OR AN ACRYLOXY GROUP DOW CORNING TORAY CO., LTD. (JP) 2007-02-22 WO disclosed
JP-H05230143-A POLYMERIZATION INHIBITOR OF POLYMERIZABLE ORGANOSILICON COMPOUND AND METHOD FOR PREVENTING ITS POLYMERIZATION SHIN ETSU CHEM CO LTD 1993-09-07 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090306370-A1 Method Of Manufacturing An Organic Silicon Compound That Contains A Methacryloxy Group Or An Acryloxy Group SIK1, SMS, SIK2 DAO 405/4885CYP3A4 1612/4885CYP2B6 3750/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.