Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | CES2 | O00748 | 2/20 | 0.40 |
| ▸ | CES1 | P23141 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1718164 | 0.77 | DAO (0.41) | LMNAMAPK1SRCCYP2D6CES2 | |
| SCHEMBL16719672 | 0.74 | KDM4E (0.43) | LMNAMAPK1CYP2D6TSHRALDH1A1 | |
| SCHEMBL6047023 | 0.71 | CES2 (0.43) | LMNAMAPK1SRCCYP2D6SLC6A2 | |
| SCHEMBL15581083 | 0.71 | ALDH1A1 (0.47) | LMNAMAPK1SRCCYP2D6CES2 | |
| SCHEMBL8026290 | 0.68 | TSHR (0.41) | LMNAMAPK1CYP2D6TSHR | |
| SCHEMBL1038340 | 0.66 | — | — | |
| Diphenylmethanol SCHEMBL10868602 | 0.64 | SMN1; SMN2 (0.61) | LMNAMAPK1SRCCYP2D6TSHR | |
| Diphenylmethanol SCHEMBL41571 | 0.64 | SMN1; SMN2 (0.61) | LMNAMAPK1SRCCYP2D6TSHR | |
| SCHEMBL2889714 | 0.64 | LMNA (0.62) | LMNAMAPK1CYP2D6SLC6A2TSHR | |
| SCHEMBL108052 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105385124-B | Carbon fiber reinforced polylactic acid 3D printing material and preparation method thereof | 浙江工业大学 | 2017-04-26 | — | — | CN | disclosed |
| EP-2406306-B1 | FLAME RETARDED POLYOLEFIN COMPOSITION | ICL IP AMERICA INC (US) | 2013-10-30 | — | — | EP | disclosed |
| US-20120121877-A1 | FLAME RETARDED POLYOLEFIN COMPOSITION | ICL-IP AMERICA INC. | 2012-05-17 | — | — | US | disclosed |
| EP-2406306-A1 | FLAME RETARDED POLYOLEFIN COMPOSITION | ICL-IP America Inc. (US) | 2012-01-18 | — | — | EP | disclosed |
| WO-2010104689-A1 | FLAME RETARDED POLYOLEFIN COMPOSITION | ICL-IP AMERICA INC. (US) | 2010-09-16 | — | — | WO | disclosed |
| US-5238979-A | Bisphenol phosphites and a phenol | ASAHI DENKA KOGYO K.K. (JP) | 1993-08-24 | — | — | US | disclosed |
| US-4532278-A | Extruded polyolefin fiber containing aromatic bromine compound, dialkylsubstituted/hydroxybenzyl/isocyanurate | HANCOCK HENRY | 1985-07-30 | — | — | US | disclosed |
| US-4532278-A | Extruded polyolefin fiber containing aromatic bromine compound, dialkylsubstituted/hydroxybenzyl/isocyanurate | HANCOCK HENRY | 1985-07-30 | — | — | US | disclosed |