Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | CPB1 | P15086 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | TLR4 | O00206 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14193328 | 0.90 | ALDH1A1 (0.52) | CA1CA2ACHEALDH1A1GAA | |
| SCHEMBL4820547 | 0.90 | ALDH1A1 (0.52) | CA1CA2ACHEALDH1A1GAA | |
| SCHEMBL9490334 | 0.83 | CA1 (0.73) | CA1CA2ACHEALDH1A1GAA | |
| SCHEMBL24324120 | 0.83 | CPB1 (0.61) | ALDH1A1GAACPB1TSHREPHX1 | |
| SCHEMBL13326281 | 0.80 | EPHX1 (0.58) | ALDH1A1GAACPB1TSHREPHX1 | |
| SCHEMBL5896895 | 0.80 | ALDH1A1 (0.57) | ALDH1A1GAACPB1TSHREPHX1 | |
| SCHEMBL18544232 | 0.80 | EPHX1 (0.58) | ALDH1A1GAACPB1TSHREPHX1 | |
| SCHEMBL5749471 | 0.80 | EPHX1 (0.58) | ALDH1A1GAACPB1TSHREPHX1 | |
| SCHEMBL5897658 | 0.80 | ALDH1A1 (0.57) | ALDH1A1GAACPB1TSHREPHX1 | |
| SCHEMBL13917140 | 0.80 | EPHX1 (0.58) | ALDH1A1GAACPB1TSHREPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2084125-B1 | AMINOBENZOCYCLOHEPTENE DERIVATIVES, METHODS FOR PREPARING THE SAME AND USES THEREOF IN THERAPY | UNIV HAUTE ALSACE (FR) | 2012-01-11 | — | — | EP | disclosed |
| US-20100069504-A1 | AMINOBENZOCYCLOHEPTENE DERIVATIVES, METHODS FOR PREPARING THE SAME AND USES THEREOF IN THERAPY | UNIVERSITE DE HAUTE ALSACE (FR) | 2010-03-18 | — | — | US | disclosed |
| EP-2084125-A1 | AMINOBENZOCYCLOHEPTENE DERIVATIVES, METHODS FOR PREPARING THE SAME AND USES THEREOF IN THERAPY | Universite De Haute Alsace (FR) | 2009-08-05 | — | — | EP | disclosed |
| WO-2008059141-A1 | AMINOBENZOCYCLOHEPTENE DERIVATIVES, METHODS FOR PREPARING THE SAME AND USES THEREOF IN THERAPY | UNIVERSITE DE HAUTE ALSACE (FR) | 2008-05-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069504-A1 | AMINOBENZOCYCLOHEPTENE DERIVATIVES, METHODS FOR PREPARING THE SAME AND USES THEREOF IN THERAPY | ANPEP, ENPEP, DNPEP | CA1 558/4885CA2 1431/4885ACHE 506/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.