Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
| ▸ | PTGES | O14684 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1718648 | 0.93 | ALDH1A1 (0.62) | MAPK1ALDH1A1HPGDCYP1A2CYP3A4 | |
| SCHEMBL1719465 | 0.91 | ALDH1A1 (0.72) | MAPK1ALDH1A1HPGDCYP1A2CYP3A4 | |
| SCHEMBL1718797 | 0.89 | RXFP1 (0.75) | MAPK1ALDH1A1HPGDCYP1A2CYP3A4 | |
| SCHEMBL1718697 | 0.88 | MAPK1 (0.69) | MAPK1ALDH1A1HPGDCYP1A2CYP3A4 | |
| SCHEMBL1718638 | 0.85 | MAPK1 (0.66) | MAPK1ALDH1A1HPGDCYP1A2CYP3A4 | |
| SCHEMBL1718356 | 0.85 | ALDH1A1 (0.74) | MAPK1ALDH1A1HPGDCYP1A2CYP3A4 | |
| SCHEMBL1718005 | 0.83 | MAPK1 (0.63) | MAPK1ALDH1A1HPGDCYP1A2CYP3A4 | |
| SCHEMBL1717999 | 0.83 | ALDH1A1 (0.77) | MAPK1ALDH1A1HPGDCYP1A2CYP3A4 | |
| SCHEMBL1718992 | 0.82 | USP2 (0.69) | MAPK1ALDH1A1HPGDCYP1A2CYP3A4 | |
| SCHEMBL1718636 | 0.82 | MAPK1 (0.62) | MAPK1ALDH1A1HPGDCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1506196-B1 | PYRAZOLOPYRIMIDINES AS SODIUM CHANNEL INHIBITORS | ICAGEN INC (US) | 2012-01-18 | — | — | EP | disclosed |