Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.38 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17186180 | 1.00 | CSNK1E (0.40) | CSNK1EHDAC8HDAC3HDAC6HDAC1 | |
| SCHEMBL1453687 | 0.85 | TDP1 (0.39) | CSNK1EHDAC8HDAC3HDAC6HDAC1 | |
| SCHEMBL1454746 | 0.80 | TDP1 (0.41) | HDAC8HDAC3HDAC6HDAC1HDAC2 | |
| SCHEMBL21870773 | 0.80 | TDP1 (0.43) | ALDH1A1TDP1 | |
| SCHEMBL29067608 | 0.79 | KCNH3 (0.39) | CSNK1EHDAC8HDAC3HDAC6HDAC1 | |
| SCHEMBL17711573 | 0.77 | HDAC8 (0.43) | CSNK1EHDAC8HDAC3HDAC6HDAC1 | |
| SCHEMBL23861793 | 0.76 | HDAC8 (0.44) | CSNK1EHDAC8HDAC3HDAC6HDAC1 | |
| SCHEMBL21499101 | 0.76 | HDAC8 (0.44) | CSNK1EHDAC8HDAC3HDAC6HDAC1 | |
| SCHEMBL4688472 | 0.76 | HDAC8 (0.44) | CSNK1EHDAC8HDAC3HDAC6HDAC1 | |
| SCHEMBL20987622 | 0.76 | HDAC8 (0.44) | CSNK1EHDAC8HDAC3HDAC6HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170029453-A1 | BIS(PHOSPHINE)-CARBODICARBENE CATALYST COMPLEXES AND METHODS OF USING THE SAME | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2017-02-02 | — | — | US | disclosed |
| WO-2015159225-A1 | BIS(PHOSPHINE)-CARBODICARBENE CATALYST COMPLEXES AND METHODS OF USING THE SAME | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2015-10-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170029453-A1 | BIS(PHOSPHINE)-CARBODICARBENE CATALYST COMPLEXES AND METHODS OF USING THE SAME | FHIT, PNMT, HNMT | CSNK1E 2364/4885HDAC8 3519/4885HDAC3 3958/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.