Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 11/20 | 0.83 |
| ▸ | CA12 | O43570 | 8/20 | 0.83 |
| ▸ | CA1 | P00915 | 5/20 | 0.83 |
| ▸ | CA2 | P00918 | 3/20 | 0.83 |
| ▸ | MMP8 | P22894 | 8/20 | 0.79 |
| ▸ | MMP14 | P50281 | 7/20 | 0.79 |
| ▸ | MMP9 | P14780 | 4/20 | 0.79 |
| ▸ | CA9 | Q16790 | 5/20 | 0.78 |
| ▸ | CA14 | Q9ULX7 | 7/20 | 0.73 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.60 |
| ▸ | FDPS | P14324 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4088119 | 0.91 | MMP2 (1.00) | MMP2CA12CA1CA2MMP8 | |
| SCHEMBL4088837 | 0.89 | MMP2 (0.68) | MMP2CA12CA1CA2MMP8 | |
| (P-Tolylamino)Methylenediphosphonic Acid SCHEMBL11570312 | 0.89 | CA12 (1.00) | MMP2CA12CA1CA2MMP8 | |
| (Phenylamino)Methylenediphosphonic Acid SCHEMBL7796889 | 0.88 | CA12 (1.00) | MMP2CA12CA1CA2MMP8 | |
| SCHEMBL7790457 | 0.84 | CA12 (0.64) | MMP2CA12CA1CA2MMP8 | |
| SCHEMBL8586225 | 0.84 | CA12 (0.65) | MMP2CA12CA1CA2MMP8 | |
| SCHEMBL17187031 | 0.81 | MMP2 (0.76) | MMP2CA12CA1CA2MMP8 | |
| SCHEMBL3981723 | 0.80 | CA12 (0.65) | MMP2CA12CA1CA2MMP8 | |
| SCHEMBL7790656 | 0.78 | FDFT1 (0.68) | MMP2CA12CA1CA2MMP8 | |
| SCHEMBL7794868 | 0.77 | FDFT1 (0.66) | MMP2CA12CA1CA2MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015159153-A1 | NOVEL BISPHOSPHONATES AND THEIR USE | WROCŁAWSKIE CENTRUM BADAŃ EIT+ SP. Z O.O. (PL) | 2015-10-22 | — | — | WO | disclosed |