Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDFT1 | P37268 | 2/20 | 0.68 |
| ▸ | MMP2 | P08253 | 9/20 | 0.59 |
| ▸ | CA12 | O43570 | 7/20 | 0.59 |
| ▸ | CA1 | P00915 | 4/20 | 0.59 |
| ▸ | CA2 | P00918 | 3/20 | 0.59 |
| ▸ | FDPS | P14324 | 4/20 | 0.56 |
| ▸ | MMP8 | P22894 | 8/20 | 0.53 |
| ▸ | MMP14 | P50281 | 7/20 | 0.53 |
| ▸ | MMP9 | P14780 | 4/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.53 |
| ▸ | CA9 | Q16790 | 4/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7794868 | 0.81 | FDFT1 (0.66) | FDFT1MMP2CA12CA1CA2 | |
| SCHEMBL17187151 | 0.78 | MMP2 (0.83) | FDFT1MMP2CA12CA1CA2 | |
| SCHEMBL7790660 | 0.77 | FDFT1 (0.65) | FDFT1MMP2CA12CA1CA2 | |
| SCHEMBL7793634 | 0.77 | FDFT1 (0.42) | FDFT1CA12CA1CA2CA9 | |
| SCHEMBL4088119 | 0.75 | MMP2 (1.00) | FDFT1MMP2CA12CA1CA2 | |
| SCHEMBL8159300 | 0.71 | FDPS (1.00) | FDFT1MMP2CA12CA1CA2 | |
| SCHEMBL4816245 | 0.70 | CA1 (0.36) | FDFT1CA12CA1CA2CA14 | |
| SCHEMBL4088837 | 0.69 | MMP2 (0.68) | FDFT1MMP2CA12CA1CA2 | |
| (P-Tolylamino)Methylenediphosphonic Acid SCHEMBL11570312 | 0.69 | CA12 (1.00) | FDFT1MMP2CA12CA1CA2 | |
| SCHEMBL7790457 | 0.69 | CA12 (0.64) | FDFT1MMP2CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0762883-B1 | PYRIDYLBISPHOSPHONATES FOR USE AS A THERAPEUTICAL AGENT | LEIRAS OY (FI) | 2001-11-14 | — | — | EP | claimed |