Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 10/20 | 1.00 |
| ▸ | CA9 | Q16790 | 4/20 | 1.00 |
| ▸ | MMP8 | P22894 | 6/20 | 0.78 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.78 |
| ▸ | MMP14 | P50281 | 5/20 | 0.78 |
| ▸ | MMP2 | P08253 | 11/20 | 0.70 |
| ▸ | FDPS | P14324 | 3/20 | 0.70 |
| ▸ | CA2 | P00918 | 2/20 | 0.70 |
| ▸ | CA1 | P00915 | 7/20 | 0.67 |
| ▸ | MMP9 | P14780 | 2/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17187151 | 0.88 | MMP2 (0.83) | CA12CA9MMP8CA14MMP14 | |
| SCHEMBL17187031 | 0.84 | MMP2 (0.76) | CA12CA9MMP8CA14MMP14 | |
| SCHEMBL4088119 | 0.80 | MMP2 (1.00) | CA12CA9MMP8CA14MMP14 | |
| SCHEMBL17187147 | 0.79 | CA12 (0.69) | CA12CA9MMP8CA14MMP14 | |
| (P-Tolylamino)Methylenediphosphonic Acid SCHEMBL11570312 | 0.78 | CA12 (1.00) | CA12CA9MMP8CA14MMP14 | |
| SCHEMBL4088837 | 0.78 | MMP2 (0.68) | CA12CA9MMP8CA14MMP14 | |
| SCHEMBL7790457 | 0.78 | CA12 (0.64) | CA12CA9MMP8CA14MMP14 | |
| SCHEMBL11450263 | 0.77 | CA9 (0.62) | CA12CA9MMP8CA14MMP14 | |
| SCHEMBL8159300 | 0.77 | FDPS (1.00) | CA12CA9MMP8CA14MMP14 | |
| SCHEMBL13458515 | 0.77 | MMP2 (0.65) | CA12CA9MMP8CA14MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3959458-A | PHOSPHONATE OR AMINO-PHOSPHORUS COMPOUND | THE PROCTER & GAMBLE COMPANY (US) | 1976-05-25 | — | — | US | claimed |
| CN-101065366-A | Dibenzyl amine compounds and derivatives | PFIZER PROD INC (US) | 2007-10-31 | — | — | CN | disclosed |
| CN-101052621-A | 4-amino substituted-2-substituted-1,2,3,4-tetrahydroquinoline compounds | PFIZER PROD INC (US) | 2007-10-10 | — | — | CN | disclosed |
| CN-1882327-A | Novel phosphorus-containing thyromimetics | METABASIS THERAPEUTICS INC (US) | 2006-12-20 | — | — | CN | disclosed |
| US-6329354-B1 | ADMINISTERING BONE ACTIVE PHOSPHONATE, ADMINISTERING ESTROGEN HORMONE | THE PROCTER & GAMBLE COMPANY | 2001-12-11 | — | — | US | disclosed |
| EP-1158987-A1 | METHODS OF INCREASING BONE VOLUME USING NON-NATURALLY-OCCURRING FP SELECTIVE AGONISTS AND ANTIRESORPTIVE COMPOUNDS | THE PROCTER & GAMBLE COMPANY (US) | 2001-12-05 | — | — | EP | disclosed |
| WO-2000051617-A1 | METHODS OF INCREASING BONE VOLUME USING NON-NATURALLY-OCCURRING FP SELECTIVE AGONISTS AND ANTIRESORPTIVE COMPOUNDS | THE PROCTER & GAMBLE COMPANY (US) | 2000-09-08 | — | — | WO | disclosed |
| EP-0802919-A4 | RAPIDLY CLEARING TECHNETIUM-99m PHOSPHONATE SKELETAL IMAGING AGENTS | MALLINCKRODT MEDICAL INC (US) | 1999-08-18 | — | — | EP | disclosed |
| US-5869471-A | Methods for the treatment of arthritis using phosphonates and NSAIDS | THE PROCTOR & GAMBLE COMPANY (US) | 1999-02-09 | — | — | US | disclosed |
| EP-0779813-A4 | PHOSPHONATES AND PARATHYROID HORMONE FOR OSTEOPOROSIS | PROCTER & GAMBLE (US) | 1998-05-06 | — | — | EP | disclosed |
| US-4137309-A | SICKLE CELL ANEMIA, GEMINAL DIPHOSPHONATE | THE PROCTER & GAMBLE COMPANY (US) | 1979-01-30 | — | — | US | disclosed |
| US-4113861-A | FOR TREATMENT OF DIABETES BY AFFECTING CARBOHYDRATE METABOLISM | THE PROCTER & GAMBLE COMPANY (US) | 1978-09-12 | — | — | US | disclosed |
| US-4113862-A | FOR TREATMENT OF DIABETES BY AFFECTING CARBOHYDRATE METABOLISM | THE PROCTER & GAMBLE COMPANY (US) | 1978-09-12 | — | — | US | disclosed |
| US-4067971-A | ORGANOPHOSPHONATE COMPOUNDS, TREATMENT OF HYPOXIA, ISCHEMIC TISSUE DISEASES | THE PROCTER & GAMBLE COMPANY (US) | 1978-01-10 | — | — | US | disclosed |
| US-4025616-A | Oral compositions for plaque, caries and calculus retardation with reduced staining tendencies | THE PROCTER & GAMBLE COMPANY (US) | 1977-05-24 | — | — | US | disclosed |
| US-RE29182-E | POLYPHOSPHONIC ACIDS | THE PROCTER & GAMBLE COMPANY (US) | 1977-04-12 | — | — | US | disclosed |
| US-3983227-A | TECHNETIUM | THE PROCTER & GAMBLE COMPANY (US) | 1976-09-28 | — | — | US | disclosed |
| US-3965254-A | Compositions for the treatment of calcific tumors | THE PROCTER & GAMBLE COMPANY (US) | 1976-06-22 | — | — | US | disclosed |
| US-3959458-A | PHOSPHONATE OR AMINO-PHOSPHORUS COMPOUND | THE PROCTER & GAMBLE COMPANY (US) | 1976-05-25 | — | — | US | disclosed |
| US-3934002-A | BIS-GUANIDE | THE PROCTER & GAMBLE COMPANY (US) | 1976-01-20 | — | — | US | disclosed |