Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3820019 | 0.86 | GAA (0.48) | GAA | |
| SCHEMBL23964494 | 0.76 | GAA (0.42) | GAA | |
| SCHEMBL329816 | 0.69 | LMNA (0.35) | — | |
| SCHEMBL10665040 | 0.68 | ALDH1A1 (0.42) | GAA | |
| SCHEMBL6026795 | 0.68 | GAA (0.41) | GAA | |
| SCHEMBL18802249 | 0.65 | — | — | |
| SCHEMBL14298979 | 0.64 | L3MBTL1 (0.48) | GAA | |
| SCHEMBL632491 | 0.63 | MEN1 (0.43) | GAA | |
| SCHEMBL147817 | 0.63 | — | — | |
| SCHEMBL4636238 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3131910-A1 | USE OF A L,3J5-TRIAZIN-2-YL PHOSPHORAMIDATE COMPOUND IN THE SYNTHESIS OF SOFOSBUVIR | Zentiva K.S. (CZ) | 2017-02-22 | — | — | EP | disclosed |
| WO-2015158317-A1 | USE OF A L,3J5-TRIAZIN-2-YL PHOSPHORAMIDATE COMPOUND IN THE SYNTHESIS OF SOFOSBUVIR | ZENTIVA, K.S. (CZ) | 2015-10-22 | — | — | WO | disclosed |
| WO-2015158317-A1 | USE OF A L,3J5-TRIAZIN-2-YL PHOSPHORAMIDATE COMPOUND IN THE SYNTHESIS OF SOFOSBUVIR | ZENTIVA, K.S. (CZ) | 2015-10-22 | — | — | WO | disclosed |