SCHEMBL6026795

SCHEMBL6026795

CC(C)(C)Oc1nc(N)nc(N)n1

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.41
KCNH2 Q12809 1/20 0.39
KDM4E B2RXH2 1/20 0.34
MAPT P10636 1/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
HSD17B10 Q99714 1/20 0.33
LMNA P02545 1/20 0.32
HSP90AA1 P07900 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.31
NUDT1 P36639 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10724686 0.84 HRH4 (0.40) GAAKCNH2HSD17B10L3MBTL1
SCHEMBL3820019 0.80 GAA (0.48) GAAKDM4E
SCHEMBL23964494 0.70 GAA (0.42) GAAKDM4EMAPTLMNAL3MBTL1
SCHEMBL7798089 0.70
SCHEMBL138352 0.69 HSD17B10 (0.44) GAAKDM4EMAPTNPC1RAB9A
SCHEMBL17187697 0.68 GAA (0.41) GAA
SCHEMBL10665040 0.68 ALDH1A1 (0.42) GAALMNA
SCHEMBL9185017 0.68 DHFR (0.32) GAANPC1RAB9AHSD17B10LMNA
SCHEMBL6396890 0.67 HSP90AA1 (0.38) NPC1RAB9ALMNAHSP90AA1
SCHEMBL3825378 0.67 GAA (0.44) GAAKDM4EL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7056965-B2 Polyoxymethylene resin composition ASAHI KASEI KABUSHIKI KAISHA (JP) 2006-06-06 US disclosed
US-20020183430-A1 Polyoxymethylene resin composition ASAHI KASEI KABUSHIKI KAISHA (JP) 2002-12-05 US disclosed