Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.37 |
| ▸ | HTR6 | P50406 | 2/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | PTPRC | P08575 | 1/20 | 0.31 |
| ▸ | TYMS | P04818 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
| ▸ | AHR | P35869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13433295 | 0.81 | CYP2A6 (0.43) | CYP2A6HTR6CYP1A2CYP2C19HTT | |
| SCHEMBL17187905 | 0.81 | CYP1A2 (0.37) | CYP2A6CYP1A2PTPRCTYMSAHR | |
| SCHEMBL5644819 | 0.79 | ALDH1A1 (0.40) | CYP2A6CYP1A2CYP2C19HTTALDH1A1 | |
| SCHEMBL17187860 | 0.78 | CYP1A2 (0.44) | CYP2A6CYP1A2ALDH1A1 | |
| SCHEMBL18428152 | 0.75 | HTR6 (0.39) | CYP2A6HTR6CYP1A2CYP2C19HTT | |
| SCHEMBL18428145 | 0.71 | ALOX5 (0.52) | — | |
| SCHEMBL17187806 | 0.71 | CYP1A2 (0.37) | CYP2A6HTR6CYP1A2AHR | |
| SCHEMBL307346 | 0.70 | PYCR1 (0.33) | CSNK2A1ALDH1A1NPSR1 | |
| SCHEMBL3860257 | 0.69 | PTGDR2 (0.31) | — | |
| SCHEMBL307319 | 0.69 | PYCR1 (0.34) | HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3134392-B1 | SULFONAMIDE DERIVATIVES AND PHARMACEUTICAL APPLICATIONS THEREOF | SUNSHINE LAKE PHARMA CO LTD (CN) | 2019-01-02 | — | — | EP | disclosed |
| US-9840482-B2 | Sulfonamide derivatives and pharmaceutical applications thereof | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2017-12-12 | — | — | US | disclosed |
| EP-3134392-A1 | SULFONAMIDE DERIVATIVES AND PHARMACEUTICAL APPLICATIONS THEREOF | Sunshine Lake Pharma Co., Ltd. (CN) | 2017-03-01 | — | — | EP | disclosed |
| US-20170037017-A1 | Sulfonamide Derivatives And Pharmaceutical Applications Thereof | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2017-02-09 | — | — | US | disclosed |
| WO-2015158313-A1 | SULFONAMIDE DERIVATIVES AND PHARMACEUTICAL APPLICATIONS THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2015-10-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170037017-A1 | Sulfonamide Derivatives And Pharmaceutical Applications Thereof | HTR6, SLC6A4, HTR2A | CYP2A6 26/4885HTR6 1/4885CSNK2A1 2271/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.