Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 3/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | FABP4 | P15090 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988045 | 0.78 | RAB9A (0.62) | GAAHPGDMAPTALDH1A1RAB9A | |
| SCHEMBL17188723 | 0.76 | GAA (0.49) | GAAHPGDMAPTALDH1A1RAB9A | |
| SCHEMBL3179153 | 0.76 | KMT2A (0.52) | GAAHPGDMAPTALDH1A1RAB9A | |
| SCHEMBL8459487 | 0.75 | HPGD (0.53) | GAAHPGDMAPTALDH1A1RAB9A | |
| SCHEMBL8452347 | 0.73 | KMT2A (0.52) | GAAHPGDMAPTALDH1A1RAB9A | |
| SCHEMBL17188766 | 0.71 | KMT2A (0.57) | HPGDMAPTALDH1A1PTGS2NPC1 | |
| Trifluoroacetic Acid SCHEMBL3171698 | 0.71 | MMP2 (0.47) | GAAHPGDMAPTALDH1A1RAB9A | |
| Trifluoroacetic Acid SCHEMBL3173811 | 0.70 | GAA (0.47) | GAAHPGDMAPTALDH1A1RAB9A | |
| Trifluoroacetic Acid SCHEMBL3179280 | 0.69 | MMP2 (0.47) | GAAHPGDMAPTALDH1A1RAB9A | |
| SCHEMBL6828220 | 0.67 | KMT2A (0.47) | GAAHPGDMAPTALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2265606-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2015-10-21 | — | — | EP | disclosed |