Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 11/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | WNT3A | P56704 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3179153 | 0.87 | KMT2A (0.52) | RAB9AMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL8459487 | 0.86 | HPGD (0.53) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL8452347 | 0.85 | KMT2A (0.52) | RAB9AMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL17188783 | 0.82 | RAB9A (0.52) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL3171698 | 0.82 | MMP2 (0.47) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL3173811 | 0.81 | GAA (0.47) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL3179280 | 0.80 | MMP2 (0.47) | RAB9AMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL6828220 | 0.78 | KMT2A (0.47) | RAB9AMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL17188733 | 0.78 | GAA (0.40) | RAB9ANPC1ALDH1A1MAPK1KDM4E | |
| SCHEMBL17188792 | 0.75 | RAB9A (0.45) | RAB9ANPC1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2813500-B1 | Intermediates for the preparation of hepatitis C virus inhibitors | BRISTOL MYERS SQUIBB CO (US) | 2016-08-17 | — | — | EP | disclosed |
| WO-2009129109-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-10-22 | — | — | WO | disclosed |