Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 10/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17188757 | 0.91 | SPHK2 (0.51) | RAB9ANPC1ALDH1A1MAPK1MEN1 | |
| SCHEMBL7988045 | 0.82 | RAB9A (0.62) | RAB9ANPC1ALDH1A1MAPK1MEN1 | |
| SCHEMBL17188792 | 0.82 | RAB9A (0.45) | RAB9ANPC1ALDH1A1MAPK1MEN1 | |
| SCHEMBL17188722 | 0.80 | CCNT1 (0.51) | NPC1MEN1KMT2APIK3CDPIK3CA | |
| SCHEMBL13524046 | 0.71 | NPSR1 (0.54) | RAB9ANPC1ALDH1A1MEN1KMT2A | |
| SCHEMBL3140112 | 0.71 | NPSR1 (0.54) | RAB9ANPC1ALDH1A1MEN1KMT2A | |
| SCHEMBL13071512 | 0.70 | DPP4 (0.58) | ALDH1A1KMT2A | |
| SCHEMBL13071511 | 0.70 | DPP4 (0.47) | PIK3CDPIK3CAPIK3CG | |
| SCHEMBL8452347 | 0.70 | KMT2A (0.52) | RAB9AALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL3179153 | 0.70 | KMT2A (0.52) | RAB9AALDH1A1MAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2265606-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2015-10-21 | — | — | EP | disclosed |