Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 11/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.41 |
| ▸ | WNT3A | P56704 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17188783 | 0.82 | RAB9A (0.52) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL7988045 | 0.75 | RAB9A (0.62) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL17188757 | 0.74 | SPHK2 (0.51) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL9892817 | 0.68 | MEN1 (0.71) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL16254980 | 0.66 | ABL1 (0.79) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL28579111 | 0.65 | MAPT (0.59) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL17188722 | 0.65 | CCNT1 (0.51) | NPC1MEN1KMT2A | |
| SCHEMBL13513636 | 0.64 | RAB9A (0.64) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL4590880 | 0.64 | KMT2A (0.59) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL9891517 | 0.64 | RAB9A (0.64) | RAB9ANPC1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2265606-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2015-10-21 | — | — | EP | disclosed |