Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS2 | Q9H2K2 | 7/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | HTR6 | P50406 | 1/20 | 0.52 |
| ▸ | TNKS | O95271 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | SULT2A1 | Q06520 | 1/20 | 0.48 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29495940 | 1.00 | TNKS2 (1.00) | TNKS2ALDH1A1KDM4EHTR1ADRD2 | |
| SCHEMBL21816546 | 0.83 | TNKS2 (0.71) | TNKS2ALDH1A1TNKSMAPTSMN1; SMN2 | |
| SCHEMBL16486612 | 0.81 | TNKS2 (0.67) | TNKS2ALDH1A1MAPTHPGDCYP3A4 | |
| SCHEMBL11919933 | 0.72 | ALDH1A1 (0.58) | TNKS2ALDH1A1TNKSMAPTSMN1; SMN2 | |
| SCHEMBL6403463 | 0.72 | CYP3A4 (0.73) | TNKS2ALDH1A1TNKSMAPTSMN1; SMN2 | |
| SCHEMBL11919912 | 0.71 | TNKS2 (0.58) | TNKS2ALDH1A1TNKSMAPTSMN1; SMN2 | |
| SCHEMBL6192012 | 0.70 | ALPG (0.69) | TNKS2ALDH1A1KDM4ETNKSMAPT | |
| SCHEMBL27242770 | 0.68 | TNKS2 (0.52) | TNKS2ALDH1A1KDM4EHTR1ADRD2 | |
| SCHEMBL6193193 | 0.68 | CDC25A (0.74) | ALDH1A1MAPTTHRBMEN1KMT2A | |
| SCHEMBL6192401 | 0.68 | ALPG (0.74) | TNKS2ALDH1A1KDM4ETNKSMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110564677-B | Inducer for inducing pluripotent stem cells to differentiate into beating cardiac muscle cells and application thereof | 上海泉生生物科技有限公司 | 2022-09-09 | — | — | CN | claimed |
| WO-2020068665-A1 | USE OF COLLAGEN BINDING DOMAINS TO DELIVER PRODUCTS TO SKIN | FABIUS BIOTECHNOLOGY (US) | 2020-04-02 | — | — | WO | claimed |
| US-10064862-B2 | Antiviral axin stabilizer | THE BOARD OF REGENTS FOR OKLAHOMA STATE UNIVERSITY (US) | 2018-09-04 | — | — | US | claimed |
| US-20170065587-A1 | ANTIVIRAL AXIN STABLIZER | THE BOARD OF REGENTS FOR OKLAHOMA STATE UNIVERSITY | 2017-03-09 | — | — | US | claimed |
| WO-2024113351-A1 | CULTURE MEDIUM, COATING MATRIX AND METHOD FOR MATURING MIDBRAIN DOPAMINERGIC PROGENITOR CELLS | NUWACELL BIOTECHNOLOGIES CO., LTD. (CN) | 2024-06-06 | — | — | WO | disclosed |
| WO-2024113354-A1 | CULTURE MEDIUM, COATING MATRIX AND METHOD FOR EXPANDING MIDBRAIN DOPAMINERGIC PROGENITOR CELLS | NUWACELL BIOTECHNOLOGIES CO., LTD. (CN) | 2024-06-06 | — | — | WO | disclosed |
| WO-2024101385-A1 | METHOD FOR PRODUCING PLURIPOTENT STEM CELLS AND METHOD FOR INDUCING DIFFERENTIATION OF PLURIPOTENT STEM CELLS | 株式会社カネカ | 2024-05-16 | — | — | WO | disclosed |
| WO-2024048555-A1 | COMBINATION DRUG | 中外製薬株式会社 | 2024-03-07 | — | — | WO | disclosed |
| WO-2023149495-A1 | PRODUCTION METHOD FOR INDUCED PLURIPOTENT STEM CELLS | 国立研究開発法人理化学研究所 | 2023-08-10 | — | — | WO | disclosed |
| US-20230203447-A1 | Methods of Producing Specialized Cardio-Like Cells from Stem Cells | UNIV EMORY (US) | 2023-06-29 | — | — | US | disclosed |
| WO-2023017806-A1 | METHOD FOR PRODUCING PLURIPOTENT STEM CELLS | 株式会社カネカ | 2023-02-16 | — | — | WO | disclosed |
| EP-4105319-A1 | METHOD FOR SUPPRESSING DIFFERENTIATION OF PLURIPOTENT STEM CELLS | Kaneka Corporation (JP) | 2022-12-21 | — | — | EP | disclosed |
| WO-2021162090-A1 | METHOD FOR SUPPRESSING DIFFERENTIATION OF PLURIPOTENT STEM CELLS | 株式会社カネカ | 2021-08-19 | — | — | WO | disclosed |
| US-10624949-B1 | Methods for treating diseases related to the wnt pathway | NATIONAL TECHNOLOGY & ENGINEERING SOLUTIONS OF SANDIA, LLC (US) | 2020-04-21 | — | — | US | disclosed |
| CN-110564677-A | inducer for inducing pluripotent stem cells to differentiate into beating cardiomyocytes and application thereof | 杭州标模生物科技有限公司 | 2019-12-13 | — | — | CN | disclosed |
| US-20190136191-A1 | Methods of Producing Specialized Cardio-Like Cells from Stem Cells | EMORY UNIVERSITY | 2019-05-09 | — | — | US | disclosed |
| US-10064862-B2 | Antiviral axin stabilizer | THE BOARD OF REGENTS FOR OKLAHOMA STATE UNIVERSITY (US) | 2018-09-04 | — | — | US | disclosed |
| US-20170065587-A1 | ANTIVIRAL AXIN STABLIZER | THE BOARD OF REGENTS FOR OKLAHOMA STATE UNIVERSITY | 2017-03-09 | — | — | US | disclosed |
| US-20150301067-A1 | METHODS AND ASSAYS FOR FACIOSCAPULOHUMERAL MUSCULAR DYSTROPHY | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) | 2015-10-22 | — | — | US | disclosed |
| US-20150301067-A1 | METHODS AND ASSAYS FOR FACIOSCAPULOHUMERAL MUSCULAR DYSTROPHY | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) | 2015-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10064862-B2 | Antiviral axin stabilizer | IRF3, AXIN2, TANK | TNKS2 10/4885ALDH1A1 2456/4885KDM4E 2840/4885 |
| US-20170065587-A1 | ANTIVIRAL AXIN STABLIZER | TNKS1BP1, TNKS, TANK | TNKS2 7/4885ALDH1A1 1947/4885KDM4E 2844/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.