Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP1B1 | Q16678 | 10/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | C1R | P00736 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10481215 | 0.79 | MAPK1 (0.41) | C1RKMT2A | |
| SCHEMBL6480259 | 0.77 | POLB (0.47) | CYP1A2KMT2ADNMT1 | |
| SCHEMBL6479992 | 0.73 | PAX8 (0.52) | CYP1A2KMT2ADNMT1 | |
| SCHEMBL13632075 | 0.72 | CYP1A2 (0.47) | CYP1A2CYP1B1HTTRXFP1KMT2A | |
| SCHEMBL623432 | 0.72 | CYP1A2 (0.47) | CYP1A2CYP1B1HTTRXFP1KMT2A | |
| SCHEMBL13631896 | 0.72 | CYP1A2 (0.47) | CYP1A2CYP1B1HTTRXFP1KMT2A | |
| SCHEMBL30052553 | 0.72 | CYP1A2 (0.47) | CYP1A2CYP1B1HTTRXFP1KMT2A | |
| SCHEMBL13631978 | 0.72 | CYP1A2 (0.47) | CYP1A2CYP1B1HTTRXFP1KMT2A | |
| SCHEMBL1720312 | 0.72 | PAX8 (0.45) | CYP1A2CYP1B1KMT2A | |
| SCHEMBL29429114 | 0.69 | RXFP1 (0.48) | CYP1A2HTTRXFP1KMT2APARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1399514-B1 | FLUORESCENT DIKETOPYRROLOPYRROLES | BASF SE (DE) | 2012-01-11 | — | — | EP | disclosed |
| US-7749404-B2 | Fluorescent diketopyrrolopyrroles | CIBA SPECIALTY CHEMICALS CORP. (US) | 2010-07-06 | — | — | US | disclosed |
| US-20060186376-A1 | Fluorescent diketopyrrolopyrroles | YAMAMOTO HIROSHI | 2006-08-24 | — | — | US | disclosed |
| US-7063806-B2 | Fluorescent diketopyrrolopyrroles | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2006-06-20 | — | — | US | disclosed |
| US-20040180235-A1 | Fluorescent diketopyrrolopyrroles | CIBA SPECIALTY CHEMICALS CORP. | 2004-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060186376-A1 | Fluorescent diketopyrrolopyrroles | DCLK1, CDKL1, TYR | CYP1A2 861/4885CYP1B1 606/4885HTT 2828/4885 |
| US-20040180235-A1 | Fluorescent diketopyrrolopyrroles | TYR, QDPR, PDK1 | CYP1A2 1319/4885CYP1B1 530/4885HTT 2515/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.