Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALPL | P05186 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TYMP | P19971 | 1/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6479992 | 0.91 | PAX8 (0.52) | POLBPTPN1PAX8ALDH1A1MAPT | |
| SCHEMBL2350283 | 0.90 | ALDH1A1 (0.43) | POLBPTPN1KDM4EALPLGAA | |
| SCHEMBL1720312 | 0.78 | PAX8 (0.45) | PAX8ALDH1A1HPGDCYP1A2CYP2A6 | |
| SCHEMBL1719328 | 0.77 | CYP1A2 (0.45) | DNMT1CYP1A2KMT2A | |
| SCHEMBL31114288 | 0.75 | ALDH1A1 (0.56) | POLBPTPN1KDM4EALPLGAA | |
| SCHEMBL10481215 | 0.73 | MAPK1 (0.41) | KDM4EGAAALDH1A1MAPTHPGD | |
| SCHEMBL15901793 | 0.72 | BCHE (0.57) | KDM4EGAAALDH1A1MAPTHPGD | |
| SCHEMBL6341548 | 0.72 | ALDH1A1 (0.57) | KDM4EALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL25302086 | 0.72 | ALDH1A1 (0.59) | POLBPTPN1KDM4EALPLGAA | |
| SCHEMBL27953 | 0.72 | ALDH1A1 (0.59) | POLBPTPN1KDM4EALPLGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050008892-A1 | Mixture of chromogens; overlapping absorption spectra; coloring high molecualr weight organic material | CIBA SPECIALTY CHEMICALS CORP. | 2005-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050008892-A1 | Mixture of chromogens; overlapping absorption spectra; coloring high molecualr weight organic material | TYR, MC1R, MC5R | POLB 1866/4885PTPN1 84/4885KDM4E 169/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.