SCHEMBL1719615

SCHEMBL1719615

CCCCCCCCCCCCCCCCCCS(=O)(=O)Nc1cccc2c3nc4nc(nc5[nH]c(nc6nc(nc([nH]3)c12)-c1ccccc1-6)c1ccccc51)-c1ccccc1-4

nearest known ligand 0.53

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PARP14 Q460N5 4/20 0.53
BRD4 O60885 1/20 0.43
ALOX5AP P20292 1/20 0.42
FEN1 P39748 1/20 0.42
BRAF P15056 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5564159 1.00 PARP14 (0.53) PARP14BRD4ALOX5APFEN1BRAF
SCHEMBL5796989 0.88 PARP14 (0.42) PARP14BRD4ALOX5APFEN1BRAF
SCHEMBL11694369 0.88 PARP14 (0.42) PARP14BRD4ALOX5APFEN1BRAF
SCHEMBL15283270 0.87 PARP14 (0.41) PARP14BRD4ALOX5APFEN1BRAF
SCHEMBL27919956 0.84 PARP14 (0.39) PARP14BRD4ALOX5APFEN1BRAF
Ciaftalan SCHEMBL5563419 0.83 RELA (0.43) PARP14BRD4
SCHEMBL9182220 0.82 UTS2R (0.46) PARP14
SCHEMBL9181704 0.82 UTS2R (0.46) PARP14
SCHEMBL28627581 0.81 PARP14 (0.36) PARP14BRD4
Ciaftalan SCHEMBL5559402 0.81 MEN1 (0.39) PARP14ALOX5APFEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7524602-B2 Low molecular weight latex and toner compositions comprising the same XEROX CORPORATION (US) 2009-04-28 US claimed
US-5164282-A Processes for the preparation of toners XEROX CORPORATION (US) 1992-11-17 US claimed
US-4454214-A FOR DEVELOPING ELECTROSTATIC IMAGES XEROX CORPORATION (US) 1984-06-12 US claimed
CN-107797399-B Support material comprising polyvinyl alcohol and use thereof in xerographic additive manufacturing 施乐公司 2023-09-22 CN disclosed
CN-116774542-A Toner containing charge control agent 施乐公司 2023-09-19 CN disclosed
CN-116774541-A Toner comprising reactive charge control agent 施乐公司 2023-09-19 CN disclosed
CN-108153121-B Metal toner comprising metal integrated particles 施乐公司 2023-06-20 CN disclosed
CN-107526256-B Toner compositions with anti-plasticizers 施乐公司 2023-04-07 CN disclosed
CN-112427274-B Co-cured film applications 波音公司 2023-03-21 CN disclosed
CN-115677897-A Latex and related compositions 施乐公司 2023-02-03 CN disclosed
CN-115677911-A Organic additives and compositions containing organic additives 施乐公司 2023-02-03 CN disclosed
US-5318431-A Process and apparatus for preparing toner particles XEROX CORPORATION (US) 1994-06-07 US disclosed
US-5288585-A Processes for the preparation of polymers XEROX CORPORATION (US) 1994-02-22 US disclosed
US-5264314-A Mixing resin monomer and polymerization initiator, curing agent, chain transfer and color, then crosslinking the suspension XEROX CORPORATION (US) 1993-11-23 US disclosed
US-5164282-A Processes for the preparation of toners XEROX CORPORATION (US) 1992-11-17 US disclosed
EP-0454980-A1 Encapsulated toners and processes thereof XEROX CORPORATION (US) 1991-11-06 EP disclosed
US-4973439-A Process for preparing toner particles XEROX CORPORATION (US) 1990-11-27 US disclosed
US-4894308-A Process for preparing electrophotographic toner XEROX CORPORATION (US) 1990-01-16 US disclosed
EP-0171911-B1 PREPARATION OF TONER PARTICLES XEROX CORPORATION (US) 1988-08-24 EP disclosed
EP-0171911-A1 Preparation of toner particles XEROX CORPORATION (US) 1986-02-19 EP disclosed