Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP14 | Q460N5 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 2/20 | 0.31 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 2/20 | 0.30 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5564159 | 0.81 | PARP14 (0.53) | PARP14BRD4 | |
| SCHEMBL1719615 | 0.81 | PARP14 (0.53) | PARP14BRD4 | |
| Ciaftalan SCHEMBL5559402 | 0.79 | MEN1 (0.39) | PARP14MEN1KMT2ATDP1THRB | |
| Ciaftalan SCHEMBL5563423 | 0.79 | MEN1 (0.39) | PARP14MEN1KMT2ATDP1THRB | |
| Ciaftalan SCHEMBL5564158 | 0.79 | MEN1 (0.39) | PARP14MEN1KMT2ATDP1THRB | |
| SCHEMBL27919956 | 0.78 | PARP14 (0.39) | PARP14MEN1KMT2ATDP1THRB | |
| SCHEMBL11694369 | 0.78 | PARP14 (0.42) | PARP14MEN1KMT2ABRD4KDM4E | |
| SCHEMBL5796989 | 0.78 | PARP14 (0.42) | PARP14MEN1KMT2ABRD4KDM4E | |
| SCHEMBL5563426 | 0.77 | PARP14 (0.34) | PARP14MEN1KMT2ATDP1THRB | |
| Ciaftalan SCHEMBL5563419 | 0.77 | RELA (0.43) | PARP14MEN1KMT2ATDP1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113461696-B | Porphyrin phthalocyanine covalent dual-functionalized graphene nonlinear nano hybrid material and preparation method thereof | 同济大学 | 2022-11-01 | — | — | CN | disclosed |
| CN-113461696-A | Porphyrin phthalocyanine covalent dual-functionalized graphene nonlinear nano hybrid material and preparation method thereof | 同济大学 | 2021-10-01 | — | — | CN | disclosed |