Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CDC7 | O00311 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24424827 | 0.84 | TDP1 (0.41) | L3MBTL1TDP1KMT2AMEN1NPSR1 | |
| SCHEMBL29585732 | 0.84 | TDP1 (0.41) | L3MBTL1TDP1KMT2AMEN1NPSR1 | |
| SCHEMBL21419164 | 0.81 | AGBL2 (0.44) | MAOBCDC7PLK4CHEK1AURKA | |
| SCHEMBL30861680 | 0.80 | TDP1 (0.58) | L3MBTL1TDP1KMT2AMEN1NPSR1 | |
| SCHEMBL9290492 | 0.80 | TDP1 (0.58) | L3MBTL1TDP1KMT2AMEN1NPSR1 | |
| SCHEMBL30861677 | 0.80 | TDP1 (0.58) | L3MBTL1TDP1KMT2AMEN1NPSR1 | |
| Ammonia Solution, Strong SCHEMBL20298816 | 0.79 | TDP1 (0.56) | L3MBTL1TDP1KMT2AMEN1NPSR1 | |
| SCHEMBL2415072 | 0.77 | ALDH1A1 (0.42) | KMT2AMEN1NPSR1MAOBALDH1A1 | |
| SCHEMBL17173641 | 0.76 | ALDH1A1 (0.36) | KMT2ACYP2C19HTTRAB9AMAOB | |
| SCHEMBL17177782 | 0.76 | CHRNB2 (0.38) | L3MBTL1KMT2AHTTMAOBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015158427-A1 | HETEROARYL SUBSTITUTED HETEROCYCLYL SULFONES | Grünenthal GmbH (DE) | 2015-10-22 | — | — | WO | disclosed |