SCHEMBL6530544

SCHEMBL6530544

C=CCSc1nnc(N)s1

nearest known ligand 0.57

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.57
FBP1 P09467 1/20 0.56
GAA P10253 1/20 0.42
MAPK1 P28482 1/20 0.42
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
HSD17B10 Q99714 1/20 0.41
MAPT P10636 1/20 0.41
ATM Q13315 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2358144 0.85 MAPT (0.46) ALDH1A1KMT2ATDP1MAPT
SCHEMBL10403369 0.80 ALDH1A1 (0.57) ALDH1A1FBP1GAAMAPK1MEN1
SCHEMBL15362563 0.76 ALDH1A1 (0.68) ALDH1A1FBP1GAAMAPK1MEN1
SCHEMBL9281254 0.76 MAPT (0.44) ALDH1A1TDP1MAPT
SCHEMBL1719700 0.76 MAPT (0.41) ALDH1A1KMT2ATDP1MAPT
SCHEMBL10980579 0.76 MAPT (0.62) ALDH1A1GAAL3MBTL1MAPT
SCHEMBL11330890 0.74 MAPT (0.40) ALDH1A1KMT2ATDP1MAPT
SCHEMBL173265 0.73 FBP1 (1.00) ALDH1A1FBP1GAAMAPK1MEN1
SCHEMBL2454347 0.72
SCHEMBL94572 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4374993-A Process for the preparation of the sulfate salt of 2-amino-5-alkylthio-1,3,4-thiadiazoles EASTMAN KODAK COMPANY (US) 1983-02-22 US claimed
CN-120424457-B Degradable packaging material and preparation method thereof 喜吉包装材料(湖北)有限公司 2026-01-30 CN disclosed
CN-120424457-A Degradable packaging material and preparation method thereof 喜吉包装材料(湖北)有限公司 2025-08-05 CN disclosed
CN-117510958-A Method for manufacturing super-hydrophobic PMMA material and super-hydrophobic PMMA material 浙江华帅特新材料科技有限公司 2024-02-06 CN disclosed
CN-111269355-A Polymer containing heterocyclic structure and application thereof 深圳市康益保健用品有限公司 2020-06-12 CN disclosed
US-6861106-B2 Dichroic dye, composition thereof, and liquid crystal composition and liquid crystal display element containing the same INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2005-03-01 US disclosed
US-20040135117-A1 Dichroic dye, composition thereof, and liquid crystal composition and liquid crystal display element containing the same INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE 2004-07-15 US disclosed
EP-0579129-B1 Thiadiazole derivatives for the treatment of depressive states CT LAB FARM SRL (IT) 1997-03-05 EP disclosed
US-5087284-A 5-substituted thiadiazole ureas and their use as herbicides RHONE-POULENC, INC. (US) 1992-02-11 US disclosed
US-4599424-A PRE-AND POSTEMERGENCE RHONE-POULENC, INC. (US) 1986-07-08 US disclosed
US-4456551-A Azo dyes from 2-amino-5-alkylthio-1,3,4-thiadiazoles and N-acyloxyalkyl-m-acylamidoanilines EASTMAN KODAK COMPANY (US) 1984-06-26 US disclosed
US-4456551-A Azo dyes from 2-amino-5-alkylthio-1,3,4-thiadiazoles and N-acyloxyalkyl-m-acylamidoanilines EASTMAN KODAK COMPANY (US) 1984-06-26 US disclosed
US-4374993-A Process for the preparation of the sulfate salt of 2-amino-5-alkylthio-1,3,4-thiadiazoles EASTMAN KODAK COMPANY (US) 1983-02-22 US disclosed
US-4374993-A Process for the preparation of the sulfate salt of 2-amino-5-alkylthio-1,3,4-thiadiazoles EASTMAN KODAK COMPANY (US) 1983-02-22 US disclosed
US-4374993-A Process for the preparation of the sulfate salt of 2-amino-5-alkylthio-1,3,4-thiadiazoles EASTMAN KODAK COMPANY (US) 1983-02-22 US disclosed
US-4182712-A 5-Substituted thiadiazole ureas MOBIL OIL CORPORATION (US) 1980-01-08 US disclosed
US-4175081-A PLANT GROWTH REGULATORS, HERBICIDES MOBIL OIL CORPORATION (US) 1979-11-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040135117-A1 Dichroic dye, composition thereof, and liquid crystal composition and liquid crystal display element containing the same CDYL, CDYL2, CCDC22 ALDH1A1 2624/4885FBP1 4556/4885GAA 3482/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.