Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | PRKDC | P78527 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 4/20 | 0.34 |
| ▸ | PLA2G4A | P47712 | 4/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.31 |
| ▸ | TTR | P02766 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17197550 | 1.00 | MMP12 (0.38) | MMP12MMP13PTGER4PRKDCNPC1 | |
| SCHEMBL15030760 | 0.94 | MMP12 (0.34) | MMP12MMP13PTGER4PRKDCNPC1 | |
| SCHEMBL17197547 | 0.93 | PLA2G2A (0.40) | MMP12MMP13PTGER4PRKDCNPC1 | |
| SCHEMBL17197504 | 0.88 | PDE6D (0.36) | PRKDCPLA2G2APLA2G4APLA2G10 | |
| SCHEMBL13827521 | 0.88 | MMP12 (0.36) | MMP12MMP13PTGER4PRKDCNPC1 | |
| SCHEMBL15030692 | 0.88 | PLA2G2A (0.36) | PRKDCNPC1RAB9AAHRMEN1 | |
| SCHEMBL13827271 | 0.87 | PLA2G2A (0.38) | PTGER4PRKDCNPC1RAB9AAHR | |
| SCHEMBL17197507 | 0.87 | ALOX5 (0.35) | PRKDCMEN1KMT2APLA2G2APLA2G4A | |
| SCHEMBL17197580 | 0.86 | PDE6D (0.37) | PRKDCPLA2G2APLA2G4APLA2G10 | |
| SCHEMBL17197515 | 0.86 | PDE6D (0.37) | PRKDCPLA2G2APLA2G4APLA2G10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10374168-B2 | Materials for electronic devices | MERCK PATENT GMBH (DE) | 2019-08-06 | — | — | US | disclosed |
| EP-3131901-B1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2018-02-07 | — | — | EP | disclosed |
| US-20170125701-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2017-05-04 | — | — | US | disclosed |
| US-20170125701-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2017-05-04 | — | — | US | disclosed |
| WO-2015158411-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2015-10-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170125701-A1 | MATERIALS FOR ELECTRONIC DEVICES | HCN2, EFNA1, EED | MMP12 4544/4885MMP13 4610/4885PTGER4 3975/4885 |
| US-10374168-B2 | Materials for electronic devices | HCN2, EFNA1, EED | MMP12 4544/4885MMP13 4610/4885PTGER4 3975/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.