Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMO | O15229 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25044243 | 0.78 | NOS1 (0.38) | CYP11B2MAPT | |
| SCHEMBL424964 | 0.78 | TRPA1 (0.46) | SLC22A12CYP11B1CYP11B2CYP2A6CYP1A2 | |
| SCHEMBL29769166 | 0.78 | TRPA1 (0.46) | SLC22A12CYP11B1CYP11B2CYP2A6CYP1A2 | |
| SCHEMBL15185701 | 0.76 | SLC22A12 (0.47) | SLC22A12CYP11B1CYP11B2CYP2A6CYP1A2 | |
| SCHEMBL13486145 | 0.76 | NR3C1 (0.61) | CYP11B1CYP11B2NR3C1 | |
| SCHEMBL16648362 | 0.76 | SLC22A12 (0.43) | SLC22A12CYP11B1CYP11B2CYP2A6CYP1A2 | |
| SCHEMBL29520791 | 0.76 | NR3C1 (0.43) | SLC22A12CYP11B1CYP11B2CYP2A6CYP1A2 | |
| SCHEMBL3657596 | 0.76 | CYP11B1 (0.47) | SLC22A12CYP11B1CYP11B2CYP2A6CYP1A2 | |
| SCHEMBL14765172 | 0.76 | HDAC8 (0.39) | CYP11B1CYP11B2CYP2A6MAPTHDAC8 | |
| SCHEMBL19772304 | 0.76 | SLC22A12 (0.40) | SLC22A12CYP11B1CYP11B2CYP2A6CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107673-A2 | CLEAVABLE DISULFIDE LINKERS AND USES THEREOF | Singular Genomics Systems, Inc. (US) | 2023-06-15 | — | — | WO | disclosed |
| EP-3892616-A1 | AROMATIC RING DERIVATIVE AS IMMUNOREGULATION AND PREPARATION METHOD AND APPLICATION OF AROMATIC RING DERIVATIVE | Shanghai Jemincare Pharmaceuticals Co., Ltd. (CN) | 2021-10-13 | — | — | EP | disclosed |
| WO-2020141439-A1 | HETEROCYCLIC COMPOUNDS AS MUTANT IDH INHIBITORS | INTEGRAL BIOSCIENCES PRIVATE LIMITED (IN) | 2020-07-09 | — | — | WO | disclosed |
| EP-2426125-A1 | 1,4 disubstituted 3 cyano pyridone derivatives and their use as positive allosteric modulators of mGluR2 receptors | Ortho-McNeil-Janssen Pharmaceuticals, Inc. (US) | 2012-03-07 | — | — | EP | disclosed |