Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 4/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 4/20 | 0.42 |
| ▸ | PKM | P14618 | 3/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18421753 | 1.00 | CYP4F2 (0.42) | CYP4F2CYP4A11PKMMMP8ALDH1A1 | |
| SCHEMBL9449272 | 0.85 | CYP4F2 (0.48) | CYP4F2CYP4A11PKMMMP8ALDH1A1 | |
| SCHEMBL9449270 | 0.85 | CYP4F2 (0.48) | CYP4F2CYP4A11PKMMMP8ALDH1A1 | |
| SCHEMBL27773595 | 0.82 | PKM (0.41) | CYP4F2CYP4A11PKMMMP8ALDH1A1 | |
| SCHEMBL79003 | 0.81 | PKM (0.43) | CYP4F2CYP4A11PKMMMP8ALDH1A1 | |
| SCHEMBL29511426 | 0.79 | CYP4F2 (0.44) | CYP4F2CYP4A11PKMMMP8ALDH1A1 | |
| SCHEMBL10386139 | 0.78 | CYP4F2 (0.43) | CYP4F2CYP4A11PKMMMP8ALDH1A1 | |
| SCHEMBL10386140 | 0.78 | CYP4F2 (0.43) | CYP4F2CYP4A11PKMMMP8ALDH1A1 | |
| SCHEMBL10385561 | 0.78 | CYP4F2 (0.43) | CYP4F2CYP4A11PKMMMP8ALDH1A1 | |
| SCHEMBL11744395 | 0.78 | CYP4F2 (0.43) | CYP4F2CYP4A11PKMMMP8ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170029453-A1 | BIS(PHOSPHINE)-CARBODICARBENE CATALYST COMPLEXES AND METHODS OF USING THE SAME | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2017-02-02 | — | — | US | disclosed |
| US-20170029453-A1 | BIS(PHOSPHINE)-CARBODICARBENE CATALYST COMPLEXES AND METHODS OF USING THE SAME | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2017-02-02 | — | — | US | disclosed |
| WO-2015159225-A1 | BIS(PHOSPHINE)-CARBODICARBENE CATALYST COMPLEXES AND METHODS OF USING THE SAME | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2015-10-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170029453-A1 | BIS(PHOSPHINE)-CARBODICARBENE CATALYST COMPLEXES AND METHODS OF USING THE SAME | FHIT, PNMT, HNMT | CYP4F2 923/4885CYP4A11 3901/4885PKM 947/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.