Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | ESR1 | P03372 | 2/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | JAK2 | O60674 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | METAP2 | P50579 | 1/20 | 0.50 |
| ▸ | METAP1 | P53582 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5825759 | 0.90 | LMNA (0.48) | MAPTKMT2ASMN1; SMN2HSD17B10ESR1 | |
| SCHEMBL38661023 | 0.88 | ESR1 (0.56) | MAPTKMT2ASMN1; SMN2ESR1ESR2 | |
| SCHEMBL2309532 | 0.85 | CYP1A2 (0.45) | SMN1; SMN2ALOX15LMNAFABP5CYP1A2 | |
| SCHEMBL38660920 | 0.84 | KMT2A (0.60) | MAPTKMT2ASMN1; SMN2HSD17B10ESR1 | |
| SCHEMBL27159853 | 0.84 | LMNA (0.47) | MAPTSMN1; SMN2HSD17B10LMNAMETAP2 | |
| SCHEMBL6631053 | 0.80 | NCF1 (0.47) | MAPTSMN1; SMN2ESR1LMNAFABP5 | |
| SCHEMBL30511914 | 0.80 | PTPN1 (0.51) | MAPTKMT2ASMN1; SMN2HSD17B10ESR1 | |
| SCHEMBL29380815 | 0.80 | NCF1 (0.47) | MAPTSMN1; SMN2ESR1LMNAFABP5 | |
| SCHEMBL9035250 | 0.80 | LMNA (0.44) | MAPTSMN1; SMN2HSD17B10LMNAALDH1A1 | |
| SCHEMBL13434056 | 0.80 | PTPN1 (0.51) | MAPTKMT2ASMN1; SMN2HSD17B10ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4330233-A1 | PHENYL -O-QUINOLINE, QUINAZOLINE, THIENOPYRIDINE, THIENOPYRIMIDINE, PYRROLOPYRIDINE, PYRROLOPYRIMIDINE COMPOUNDS HAVING ANTICANCER ACTIVITY | Chengdu Anticancer Bioscience, Ltd. (CN) | 2024-03-06 | — | — | EP | disclosed |
| WO-2015160125-A1 | NOVEL PREPARATION METHOD OF QUINOLINE N-OXIDE DERIVATIVE WITH AMIDE GROUP | INSTITUTE FOR BASIC SCIENCE (KR) | 2015-10-22 | — | — | WO | disclosed |