Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | NCF1 | P14598 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17199398 | 0.84 | MAPT (0.54) | LMNAF2ARCYP1A2NCOA3 | |
| SCHEMBL5825759 | 0.78 | LMNA (0.48) | LMNAARSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL2309532 | 0.76 | CYP1A2 (0.45) | LMNACYP1A2LOXL2SMN1; SMN2NCF1 | |
| SCHEMBL11881720 | 0.75 | LOXL2 (0.52) | CYP1A2LOXL2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL29611759 | 0.74 | LMNA (0.70) | LMNAF2SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL38661023 | 0.74 | ESR1 (0.56) | LMNASMN1; SMN2NPC1RAB9AALDH1A1 | |
| Carbamic Acid SCHEMBL29034270 | 0.73 | ALOX15 (0.54) | LMNASMN1; SMN2RAB9AALDH1A1MAPT | |
| SCHEMBL2112736 | 0.73 | KDM4E (0.58) | CYP1A2LOXL2SMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL28683734 | 0.73 | TDP1 (0.51) | LMNACYP1A2LOXL2ALDH1A1MAPT | |
| SCHEMBL14877345 | 0.72 | LMNA (0.59) | LMNAF2SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4330233-A1 | PHENYL -O-QUINOLINE, QUINAZOLINE, THIENOPYRIDINE, THIENOPYRIMIDINE, PYRROLOPYRIDINE, PYRROLOPYRIMIDINE COMPOUNDS HAVING ANTICANCER ACTIVITY | Chengdu Anticancer Bioscience, Ltd. (CN) | 2024-03-06 | — | — | EP | disclosed |