SCHEMBL17199698

SCHEMBL17199698

COc1ccc(N(c2ccc(C=C3c4cc(Br)ccc4-c4ccc(Br)cc43)cc2)c2ccc(-c3ccc(N(c4ccc(C=C5c6cc(Br)ccc6-c6ccc(Br)cc65)cc4)c4ccc(OC)cc4)cc3)cc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIM1 P11309 3/20 0.44
CSNK2A1 P68400 1/20 0.44
AURKB Q96GD4 1/20 0.44
MAP4K5 Q9Y4K4 1/20 0.44
APP P05067 1/20 0.43
ALOX5 P09917 1/20 0.39
PIM3 Q86V86 2/20 0.37
PIM2 Q9P1W9 2/20 0.37
MAOB P27338 3/20 0.37
MAOA P21397 1/20 0.37
METAP1 P53582 1/20 0.37
LCK P06239 1/20 0.36
PRKACA P17612 1/20 0.36
PRKACG P22612 1/20 0.36
PRKACB P22694 1/20 0.36
MAPT P10636 1/20 0.36
HDAC3 O15379 1/20 0.35
HDAC4 P56524 1/20 0.35
HDAC1 Q13547 1/20 0.35
HDAC7 Q8WUI4 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17209464 0.89 METAP1 (0.40) PIM1CSNK2A1AURKBMAP4K5MAOB
SCHEMBL14421802 0.88 APP (0.51) PIM1CSNK2A1AURKBMAP4K5APP
SCHEMBL17209533 0.85 METAP1 (0.43) MAOBMAOAMETAP1LCKMAPT
SCHEMBL17199705 0.85 LCK (0.40) APPMAOBMAOALCKMAPT
SCHEMBL12890209 0.81 MAPT (0.42) CSNK2A1APPMAOBMAOALCK
SCHEMBL17199710 0.81 MAPT (0.42) CSNK2A1APPMAOBMAOALCK
SCHEMBL17209483 0.80 RELA (0.46) ALOX5MAOBMAOAMETAP1
SCHEMBL17209480 0.80 TRPA1 (0.42) APPMAOBMAOAMETAP1MAPT
SCHEMBL17199706 0.79 PTPRC (0.39) APPLCKMAPTMEN1KMT2A
SCHEMBL14646306 0.79 S100A4 (0.45) APPMAPTHDAC4HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015161989-A1 HOLE-TRANSPORT MATERIALS FOR ORGANIC SOLAR CELLS OR ORGANIC OPTICAL SENSORS BASF SE (DE) 2015-10-29 WO disclosed
WO-2015161989-A1 HOLE-TRANSPORT MATERIALS FOR ORGANIC SOLAR CELLS OR ORGANIC OPTICAL SENSORS BASF SE (DE) 2015-10-29 WO disclosed
EP-2937399-A1 Hole-transport materials for organic solar cells or organic optical sensors BASF SE (DE) 2015-10-28 EP disclosed
EP-2937399-A1 Hole-transport materials for organic solar cells or organic optical sensors BASF SE (DE) 2015-10-28 EP disclosed