SCHEMBL17199710

SCHEMBL17199710

Cc1ccc(N(c2ccc(C=C3c4cc(Br)ccc4-c4ccc(Br)cc43)cc2)c2ccc(C=C3c4cc(Br)ccc4-c4ccc(Br)cc43)cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.42
POLB P06746 3/20 0.42
MDM2 Q00987 3/20 0.42
L3MBTL1 Q9Y468 3/20 0.42
KDM4E B2RXH2 1/20 0.42
RECQL P46063 1/20 0.42
RAB9A P51151 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
APP P05067 2/20 0.37
CSNK2A2 P19784 1/20 0.37
CSNK2B P67870 1/20 0.37
CSNK2A1 P68400 1/20 0.37
CSNK2A3 Q8NEV1 1/20 0.37
LCK P06239 1/20 0.35
ALDH1A1 P00352 3/20 0.35
S100A4 P26447 1/20 0.34
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
MAOA P21397 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12890209 1.00 MAPT (0.42) MAPTPOLBMDM2L3MBTL1KDM4E
SCHEMBL17199705 0.92 LCK (0.40) MAPTPOLBMDM2L3MBTL1RAB9A
SCHEMBL17199706 0.86 PTPRC (0.39) MAPTPOLBMDM2L3MBTL1KDM4E
SCHEMBL3814228 0.83 APP (0.51) MAPTRAB9ANPSR1TDP1APP
SCHEMBL1242523 0.82 ALDH1A1 (0.49) MAPTPOLBMDM2L3MBTL1KDM4E
SCHEMBL17199708 0.82 S100A4 (0.48) POLBRAB9AAPPLCKS100A4
SCHEMBL17199698 0.81 PIM1 (0.44) MAPTAPPCSNK2A1LCKMEN1
SCHEMBL17209483 0.78 RELA (0.46) MAOAMAOB
SCHEMBL17205037 0.74 PTPRC (0.35) LCKMEN1KMT2AERBB2
SCHEMBL17199713 0.74 LCK (0.50) NPSR1APPLCKS100A4MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015161989-A1 HOLE-TRANSPORT MATERIALS FOR ORGANIC SOLAR CELLS OR ORGANIC OPTICAL SENSORS BASF SE (DE) 2015-10-29 WO disclosed
WO-2015161989-A1 HOLE-TRANSPORT MATERIALS FOR ORGANIC SOLAR CELLS OR ORGANIC OPTICAL SENSORS BASF SE (DE) 2015-10-29 WO disclosed
EP-2937399-A1 Hole-transport materials for organic solar cells or organic optical sensors BASF SE (DE) 2015-10-28 EP disclosed
EP-2937399-A1 Hole-transport materials for organic solar cells or organic optical sensors BASF SE (DE) 2015-10-28 EP disclosed