Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 13/20 | 0.47 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2586864 | 0.83 | MAOA (0.64) | MAOABCHENOX1MAPTHPGD | |
| SCHEMBL26374038 | 0.80 | MAOA (0.46) | MAOABCHENOX1GAAMAPT | |
| SCHEMBL1718054 | 0.76 | MAOA (0.64) | MAOABCHENOX1PTGS1PTGS2 | |
| SCHEMBL19798777 | 0.73 | BCHE (0.37) | MAOABCHENOX1GAAMAPT | |
| SCHEMBL14244233 | 0.73 | MAOA (0.54) | MAOABCHENOX1PTGS1PTGS2 | |
| SCHEMBL29824891 | 0.73 | MAOA (0.54) | MAOABCHENOX1PTGS1PTGS2 | |
| SCHEMBL5435400 | 0.72 | BCHE (0.47) | BCHENOX1GAAACHEHTR2C | |
| SCHEMBL5435395 | 0.71 | MEN1 (0.71) | BCHENOX1MAPTNPSR1KDM1A | |
| SCHEMBL19798774 | 0.71 | KDM1A (0.37) | MAOABCHEMAPTHPGDALOX12 | |
| SCHEMBL19798773 | 0.71 | BCHE (0.34) | MAOABCHENOX1PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8148565-B2 | Method of manufacturing an organic silicon compound that contains a methacryloxy group or an acryloxy group | DOW CORNING TORAY COMPANY, LTD. (JP) | 2012-04-03 | — | — | US | disclosed |
| EP-1915384-B1 | A METHOD OF MANUFACTURING AN ORGANIC SILICON COMPOUND THAT CONTAINS A METHACRYLOXY GROUP OR AN ACRYLOXY GROUP | DOW CORNING TORAY CO LTD (JP) | 2012-01-11 | — | — | EP | disclosed |
| US-20090306370-A1 | Method Of Manufacturing An Organic Silicon Compound That Contains A Methacryloxy Group Or An Acryloxy Group | DOW TORAY CO., LTD. (JP) | 2009-12-10 | — | — | US | disclosed |
| US-4556476-A | Method for minimizing fouling of heat exchanger | ATLANTIC RICHFIELD COMPANY (US) | 1985-12-03 | — | — | US | disclosed |
| US-4529500-A | Using a diphenolthiazine compound | ATLANTIC RICHFIELD (US) | 1985-07-16 | — | — | US | disclosed |
| US-4511457-A | N,N*-PHENOTHIAZINE DIMER, TERT-ALKYL CATECHOL OR HYDROQUINONE | ATLANTIC RICHFIELD COMPANY (US) | 1985-04-16 | — | — | US | disclosed |
| US-4487981-A | ADDING N,N' DIMER OF PHENOTHIAZINE AND AN ALKYL CATECHOL OR ALKYL HYDROQUINONE | ATLANTIC RICHFIELD COMPANY (US) | 1984-12-11 | — | — | US | disclosed |
| US-4487982-A | ADDING N,N'-DIMER OF PHENOTHIAZINE AND MONOOR DITERTIARY ALKYL PHENOL | ATLANTIC RICHFIELD COMPANY (US) | 1984-12-11 | — | — | US | disclosed |
| US-4465882-A | N,N*-PHENOTHIAZING DIMER AND HYDROXYLAMINE DERIVATIVE | ATLANTIC RICHFIELD COMPANY (US) | 1984-08-14 | — | — | US | disclosed |
| US-4465881-A | N,N*-DIMER OF PHENOTHIAZINE | ATLANTIC RICHFIELD COMPANY (US) | 1984-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090306370-A1 | Method Of Manufacturing An Organic Silicon Compound That Contains A Methacryloxy Group Or An Acryloxy Group | SIK1, SMS, SIK2 | MAOA 1279/4885BCHE 4141/4885NOX1 3375/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.