Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | HTT | P42858 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALPG | P10696 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19798776 | 0.72 | MAPT (0.34) | ALDH1A1MAPTHTTMEN1KMT2A | |
| SCHEMBL19798773 | 0.72 | BCHE (0.34) | ALDH1A1HTTMEN1KMT2ACYP1A2 | |
| SCHEMBL1720092 | 0.71 | MAOA (0.50) | KDM1AMAPTMEN1KMT2ANPSR1 | |
| SCHEMBL19798777 | 0.71 | BCHE (0.37) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL19798778 | 0.69 | MAPT (0.34) | MAPTLMNA | |
| SCHEMBL2586864 | 0.69 | MAOA (0.64) | KDM1AALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL5435395 | 0.69 | MEN1 (0.71) | KDM1AALDH1A1MAPTHTTMEN1 | |
| SCHEMBL18610703 | 0.69 | KDM1A (0.44) | KDM1AALDH1A1MAPTHTTMEN1 | |
| SCHEMBL23308369 | 0.68 | KDM1A (0.48) | KDM1AALDH1A1MAPTHTTMEN1 | |
| SCHEMBL28242942 | 0.68 | KDM1A (0.48) | KDM1AALDH1A1MAPTHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10854911-B2 | 1,9,10-substituted phenothiazine derivatives with strained radical cations and use thereof | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2020-12-01 | — | — | US | disclosed |
| US-20180026297-A1 | 1,9,10-SUBSTITUTED PHENATHIAZINE DERIVATIVES WITH STRAINED RADICAL CATIONS AND USE THEREOF | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION | 2018-01-25 | — | — | US | disclosed |
| US-20180026297-A1 | 1,9,10-SUBSTITUTED PHENATHIAZINE DERIVATIVES WITH STRAINED RADICAL CATIONS AND USE THEREOF | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION | 2018-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10854911-B2 | 1,9,10-substituted phenothiazine derivatives with strained radical cations and use thereof | SLC6A9, PEX3, PAOX | KDM1A 3258/4885ALDH1A1 1145/4885MAPT 4337/4885 |
| US-20180026297-A1 | 1,9,10-SUBSTITUTED PHENATHIAZINE DERIVATIVES WITH STRAINED RADICAL CATIONS AND USE THEREOF | PFAS, SLC6A9, PEX3 | KDM1A 2694/4885ALDH1A1 1765/4885MAPT 4553/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.