Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 5/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.33 |
| ▸ | MAOA | P21397 | 3/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.32 |
| ▸ | SCN4A | P35499 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | SCN1A | P35498 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | HTR2B | P41595 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.32 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28939779 | 0.90 | TSHR (0.40) | BCHEPTGS1LMNATSHRCYP1A2 | |
| SCHEMBL22600935 | 0.73 | ALDH1A1 (0.34) | TSHRCYP1A2ALDH1A1ALOX15MEN1 | |
| SCHEMBL5435400 | 0.73 | BCHE (0.47) | BCHECYP2D6TSHRHTR2AHTR2B | |
| SCHEMBL19798774 | 0.72 | KDM1A (0.37) | BCHEPTGS1MAOAPTGS2CYP2D6 | |
| SCHEMBL22600834 | 0.72 | MAPT (0.32) | ALDH1A1 | |
| SCHEMBL19798777 | 0.71 | BCHE (0.37) | BCHEMAOALMNATSHRNOX1 | |
| SCHEMBL1720092 | 0.71 | MAOA (0.50) | BCHEPTGS1MAOAPTGS2SLC6A4 | |
| SCHEMBL2586864 | 0.69 | MAOA (0.64) | BCHEMAOALMNASLC6A4HTR2B | |
| SCHEMBL23072132 | 0.68 | MAOA (0.43) | BCHEPTGS1MAOAPTGS2CYP2D6 | |
| SCHEMBL30184394 | 0.68 | MAOA (0.58) | BCHEPTGS1MAOAPTGS2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10854911-B2 | 1,9,10-substituted phenothiazine derivatives with strained radical cations and use thereof | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2020-12-01 | — | — | US | disclosed |
| US-20180026297-A1 | 1,9,10-SUBSTITUTED PHENATHIAZINE DERIVATIVES WITH STRAINED RADICAL CATIONS AND USE THEREOF | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION | 2018-01-25 | — | — | US | disclosed |
| US-20180026297-A1 | 1,9,10-SUBSTITUTED PHENATHIAZINE DERIVATIVES WITH STRAINED RADICAL CATIONS AND USE THEREOF | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION | 2018-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10854911-B2 | 1,9,10-substituted phenothiazine derivatives with strained radical cations and use thereof | SLC6A9, PEX3, PAOX | BCHE 4376/4885PTGS1 3618/4885MAOA 2172/4885 |
| US-20180026297-A1 | 1,9,10-SUBSTITUTED PHENATHIAZINE DERIVATIVES WITH STRAINED RADICAL CATIONS AND USE THEREOF | PFAS, SLC6A9, PEX3 | BCHE 3640/4885PTGS1 2929/4885MAOA 1421/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.