Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30359275 | 0.87 | ALDH1A1 (0.42) | SIGMAR1MAPTHTTL3MBTL1ALDH1A1 | |
| SCHEMBL4203004 | 0.85 | CYP3A4 (0.43) | SIGMAR1KMT2ACYP3A4TDP1KCNN4 | |
| SCHEMBL2155415 | 0.83 | KCNN4 (0.44) | SIGMAR1CYP3A4TDP1KCNN4MAPT | |
| Propane SCHEMBL2359635 | 0.78 | CYP3A4 (0.41) | SIGMAR1CYP3A4TDP1KCNN4MAPT | |
| SCHEMBL9907211 | 0.77 | POLB (0.41) | KMT2ACYP3A4TDP1MTORRAB9A | |
| SCHEMBL7636331 | 0.77 | KIF11 (0.42) | KMT2ACYP3A4TDP1MTORRAB9A | |
| SCHEMBL9907231 | 0.77 | TAAR1 (0.42) | SIGMAR1KMT2ARAB9APOLBTAAR1 | |
| SCHEMBL28580058 | 0.76 | NPC1 (0.50) | SIGMAR1CYP3A4MAPTRAB9ALMNA | |
| SCHEMBL321882 | 0.72 | TDP1 (0.50) | CYP3A4TDP1MTORRAB9AGRM7 | |
| SCHEMBL13836509 | 0.71 | KCNN4 (0.43) | SIGMAR1CYP3A4TDP1KCNN4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105238364-B | Organic high-temperature heat-conductive liquid | 奢派热力科技（上海）有限公司 | 2018-05-25 | — | — | CN | claimed |
| CN-105238364-B | Organic high-temperature heat-conductive liquid | 奢派热力科技（上海）有限公司 | 2018-05-25 | — | — | CN | disclosed |
| US-9308528-B2 | Nickel-based complexes and their use in a process for the transformation of olefins | UNIVERSITEIT VAN AMSTERDAM (NL) | 2016-04-12 | — | — | US | disclosed |
| US-9308528-B2 | Nickel-based complexes and their use in a process for the transformation of olefins | UNIVERSITEIT VAN AMSTERDAM (NL) | 2016-04-12 | — | — | US | disclosed |
| US-9308528-B2 | Nickel-based complexes and their use in a process for the transformation of olefins | UNIVERSITEIT VAN AMSTERDAM (NL) | 2016-04-12 | — | — | US | disclosed |
| EP-2939743-A1 | NOVEL NICKEL-BASED COMPLEXES AND USE THEREOF IN A METHOD FOR TRANSFORMING OLEFINS | IFP Energies nouvelles (FR) | 2015-11-04 | — | — | EP | disclosed |
| EP-2939743-A1 | NOVEL NICKEL-BASED COMPLEXES AND USE THEREOF IN A METHOD FOR TRANSFORMING OLEFINS | IFP Energies nouvelles (FR) | 2015-11-04 | — | — | EP | disclosed |
| US-20150306589-A1 | NOVEL NICKEL-BASED COMPLEXES AND THEIR USE IN A PROCESS FOR THE TRANSFORMATION OF OLEFINS | UNIVERSITEIT VAN AMSTERDAM (NL) | 2015-10-29 | — | — | US | disclosed |
| US-20150306589-A1 | NOVEL NICKEL-BASED COMPLEXES AND THEIR USE IN A PROCESS FOR THE TRANSFORMATION OF OLEFINS | UNIVERSITEIT VAN AMSTERDAM (NL) | 2015-10-29 | — | — | US | disclosed |
| US-20150306589-A1 | NOVEL NICKEL-BASED COMPLEXES AND THEIR USE IN A PROCESS FOR THE TRANSFORMATION OF OLEFINS | UNIVERSITEIT VAN AMSTERDAM (NL) | 2015-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150306589-A1 | NOVEL NICKEL-BASED COMPLEXES AND THEIR USE IN A PROCESS FOR THE TRANSFORMATION OF OLEFINS | TRRAP, NISCH, PORCN | SIGMAR1 3649/4885KMT2A 1866/4885CYP3A4 518/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.