Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 8/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.56 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.56 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.56 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.56 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.56 |
| ▸ | GSK3B | P49841 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17201724 | 1.00 | APP (0.60) | APPHPGDKDM4EALDH1A1HTT | |
| SCHEMBL17201731 | 0.96 | APP (0.60) | APPHPGDKDM4EALDH1A1HTT | |
| SCHEMBL17201732 | 0.96 | APP (0.60) | APPHPGDKDM4EALDH1A1HTT | |
| SCHEMBL17201736 | 0.91 | GSK3B (0.56) | APPHPGDKDM4EALDH1A1HTT | |
| SCHEMBL17201737 | 0.91 | GSK3B (0.56) | APPHPGDKDM4EALDH1A1HTT | |
| SCHEMBL17201746 | 0.86 | APP (0.61) | APPHPGDKDM4EALDH1A1HTT | |
| SCHEMBL17201748 | 0.86 | APP (0.61) | APPHPGDKDM4EALDH1A1HTT | |
| SCHEMBL38661511 | 0.85 | NQO2 (0.66) | APPGSK3BTTRCYP1A1NQO2 | |
| SCHEMBL28440296 | 0.85 | APP (0.61) | APPHPGDKDM4EALDH1A1HTT | |
| SCHEMBL17201750 | 0.84 | APP (0.53) | APPHPGDKDM4EALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11634375-B2 | Prenylated hydroxystilbenes | Kynan Duke IP, LLC (US) | 2023-04-25 | — | — | US | disclosed |
| US-20220380285-A1 | PRENYLATED HYDROXYSTILBENES | Kynan Duke IP, LLC (US) | 2022-12-01 | — | — | US | disclosed |
| US-11352310-B2 | Prenylated hydroxystilbenes | Kynan Duke IP, LLC (US) | 2022-06-07 | — | — | US | disclosed |
| EP-2709975-B1 | PRENYLATED HYDROXYSTILBENES | KYNAN DUKE IP LLC (US) | 2022-01-12 | — | — | EP | disclosed |
| US-20200331833-A1 | PRENYLATED HYDROXYSTILBENES | THE UNIVERSITY OF SYDNEY (AU) | 2020-10-22 | — | — | US | disclosed |
| CN-107266297-B | Prenylated hydroxystilbenes, pharmaceutical compositions containing the same, use and preparation method thereof | 悉尼大学 | 2020-10-16 | — | — | CN | disclosed |
| US-10696615-B2 | Prenylated hydroxystilbenes | THE UNIVERSITY OF SYDNEY (AU) | 2020-06-30 | — | — | US | disclosed |
| US-20190194105-A1 | PRENYLATED HYDROXYSTILBENES | THE UNIVERSITY OF SYDNEY (AU) | 2019-06-27 | — | — | US | disclosed |
| US-10196335-B2 | Prenylated hydroxystilbenes | THE UNIVERSITY OF SYDNEY (AU) | 2019-02-05 | — | — | US | disclosed |
| US-20150307429-A1 | PRENYLATED HYDROXYSTILBENES | Kynan Duke IP, LLC | 2015-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10196335-B2 | Prenylated hydroxystilbenes | HMGB2, CYP51A1, CYP8B1 | APP 1081/4885HPGD 110/4885KDM4E 3528/4885 |
| US-20200331833-A1 | PRENYLATED HYDROXYSTILBENES | HSD11B1, HSD3B1, CYP8B1 | APP 1819/4885HPGD 172/4885KDM4E 4261/4885 |
| US-20220380285-A1 | PRENYLATED HYDROXYSTILBENES | HSD11B1, HSD3B1, CYP8B1 | APP 1819/4885HPGD 172/4885KDM4E 4261/4885 |
| US-20150307429-A1 | PRENYLATED HYDROXYSTILBENES | HMGB2, CYP51A1, CYP8B1 | APP 1081/4885HPGD 110/4885KDM4E 3528/4885 |
| US-10696615-B2 | Prenylated hydroxystilbenes | HSD11B1, CYP8B1, NR1H2 | APP 2321/4885HPGD 268/4885KDM4E 3865/4885 |
| US-11352310-B2 | Prenylated hydroxystilbenes | HSD11B1, HSD3B1, CYP8B1 | APP 1819/4885HPGD 172/4885KDM4E 4261/4885 |
| US-20190194105-A1 | PRENYLATED HYDROXYSTILBENES | HSD11B1, CYP8B1, NR1H2 | APP 2321/4885HPGD 268/4885KDM4E 3865/4885 |
| US-11634375-B2 | Prenylated hydroxystilbenes | HCLS1, IWS1, UTS2R | APP 2779/4885HPGD 440/4885KDM4E 3457/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.