Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 5/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 3/20 | 0.36 |
| ▸ | F10 | P00742 | 3/20 | 0.36 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5444324 | 0.85 | ALDH1A1 (0.48) | HPGDKMT2AALDH1A1AKR1C3L3MBTL1 | |
| SCHEMBL17205569 | 0.82 | MAPT (0.56) | KMT2AALDH1A1 | |
| SCHEMBL16730262 | 0.81 | ALDH1A1 (0.52) | HPGDMEN1KMT2AALDH1A1AKR1C3 | |
| SCHEMBL17205575 | 0.77 | SIRT6 (0.61) | HPGDALDH1A1 | |
| SCHEMBL8357983 | 0.76 | ALDH1A1 (0.41) | MEN1KMT2AALDH1A1L3MBTL1F2 | |
| SCHEMBL17507092 | 0.75 | ALDH1A1 (0.46) | HPGDALDH1A1BRD9AKR1C3F2 | |
| SCHEMBL8360878 | 0.75 | DRD2 (0.43) | MEN1KMT2AALDH1A1L3MBTL1TSHR | |
| SCHEMBL18028120 | 0.75 | ALDH1A1 (0.42) | HPGDMEN1KMT2AALDH1A1F10 | |
| SCHEMBL16730424 | 0.74 | ALDH1A1 (0.49) | HPGDMEN1KMT2AALDH1A1BRD9 | |
| SCHEMBL5441070 | 0.74 | MEN1 (0.36) | MEN1KMT2AALDH1A1AKR1C3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015162551-A1 | PROCESS FOR THE PREPARATION OF APIXABAN | MYLAN LABORATORIES LTD (IN) | 2015-10-29 | — | — | WO | disclosed |
| WO-2015162551-A1 | PROCESS FOR THE PREPARATION OF APIXABAN | MYLAN LABORATORIES LTD (IN) | 2015-10-29 | — | — | WO | disclosed |