Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | GFER | P55789 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.56 |
| ▸ | PTK2B | Q14289 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.56 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17205684 | 0.82 | HPGD (0.48) | ALDH1A1KMT2A | |
| SCHEMBL17205575 | 0.82 | SIRT6 (0.61) | MAPTALDH1A1HRH4LMNASIRT6 | |
| SCHEMBL15731795 | 0.82 | PIK3R1 (0.39) | MAPTKDM4EGFERALDH1A1GAA | |
| SCHEMBL8357983 | 0.76 | ALDH1A1 (0.41) | MAPTKDM4EALDH1A1KMT2ARECQL | |
| SCHEMBL8360878 | 0.75 | DRD2 (0.43) | MAPTKDM4EALDH1A1KMT2ARECQL | |
| SCHEMBL56547 | 0.73 | MAPT (1.00) | MAPTKDM4EGFERALDH1A1GAA | |
| SCHEMBL6414948 | 0.73 | MAPT (1.00) | MAPTKDM4EGFERALDH1A1GAA | |
| SCHEMBL6151538 | 0.73 | MAPT (1.00) | MAPTKDM4EGFERALDH1A1GAA | |
| SCHEMBL5441070 | 0.73 | MEN1 (0.36) | MAPTKDM4EALDH1A1GAAKMT2A | |
| SCHEMBL17576245 | 0.72 | AKR1C3 (0.44) | MAPTKDM4EALDH1A1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015162551-A1 | PROCESS FOR THE PREPARATION OF APIXABAN | MYLAN LABORATORIES LTD (IN) | 2015-10-29 | — | — | WO | disclosed |
| WO-2015162551-A1 | PROCESS FOR THE PREPARATION OF APIXABAN | MYLAN LABORATORIES LTD (IN) | 2015-10-29 | — | — | WO | disclosed |