Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 7/20 | 0.51 |
| ▸ | FAAH | O00519 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.38 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.38 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.38 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18502952 | 0.92 | CYP11B2 (0.52) | CYP11B2FAAHLMNAGPR119SMARCA2 | |
| SCHEMBL18566765 | 0.77 | CYP11B2 (0.66) | CYP11B2FAAH | |
| SCHEMBL17207637 | 0.76 | CYP11B2 (0.65) | CYP11B2FAAH | |
| SCHEMBL17207636 | 0.75 | CYP11B2 (0.61) | CYP11B2 | |
| SCHEMBL18502899 | 0.70 | CYP11B2 (0.52) | CYP11B2GPR119MAPTPTPN11 | |
| SCHEMBL17207585 | 0.70 | CYP11B2 (0.59) | CYP11B2GPR119PIK3CAMAPT | |
| SCHEMBL3269713 | 0.69 | FAAH (0.61) | FAAHLMNAGPR119SMARCA2SMARCA4 | |
| SCHEMBL18502914 | 0.69 | SCD5 (0.45) | CYP11B2GPR119SMARCA2SMARCA4PBRM1 | |
| SCHEMBL20293573 | 0.68 | GPR119 (0.58) | LMNAGPR119CCNT1CDK9MAPT | |
| SCHEMBL17207592 | 0.68 | CYP11B2 (0.59) | CYP11B2GPR119PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015163427-A1 | NOVEL DISUBSTITUTED 1, 2, 4-TRIAZINE COMPOUND | 田辺三菱製薬株式会社 | 2015-10-29 | — | — | WO | disclosed |