Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 8/20 | 1.00 |
| ▸ | MAPT | P10636 | 8/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 5/20 | 1.00 |
| ▸ | ALOX15 | P16050 | 4/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 1.00 |
| ▸ | HPGD | P15428 | 3/20 | 1.00 |
| ▸ | TSHR | P16473 | 3/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 1.00 |
| ▸ | POLB | P06746 | 4/20 | 0.77 |
| ▸ | MEN1 | O00255 | 2/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.77 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.73 |
| ▸ | CASP1 | P29466 | 1/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.68 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13186479 | 0.84 | MAPT (1.00) | L3MBTL1MAPTALDH1A1MAPK1ALOX15 | |
| SCHEMBL25244921 | 0.84 | L3MBTL1 (0.78) | L3MBTL1MAPTALDH1A1MAPK1ALOX15 | |
| SCHEMBL15347242 | 0.83 | L3MBTL1 (0.97) | L3MBTL1MAPTALDH1A1MAPK1ALOX15 | |
| SCHEMBL13912138 | 0.80 | BCL2A1 (0.75) | L3MBTL1MAPTALDH1A1MAPK1ALOX15 | |
| SCHEMBL5682657 | 0.79 | L3MBTL1 (0.66) | L3MBTL1MAPTALDH1A1MAPK1ALOX15 | |
| SCHEMBL13912151 | 0.78 | BCL2A1 (0.77) | L3MBTL1MAPTALDH1A1MAPK1ALOX15 | |
| SCHEMBL2488181 | 0.76 | ALDH1A1 (0.59) | L3MBTL1MAPTALDH1A1MAPK1ALOX15 | |
| SCHEMBL13186473 | 0.72 | RAD51 (1.00) | L3MBTL1MAPTALDH1A1MAPK1ALOX15 | |
| SCHEMBL13912142 | 0.72 | BCL2A1 (1.00) | L3MBTL1MAPTALDH1A1MAPK1ALOX15 | |
| SCHEMBL17208335 | 0.71 | RAD51 (0.64) | L3MBTL1MAPTALDH1A1MAPK1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150306069-A1 | METHODS AND COMPOSITIONS INVOLVING RAD51 INHIBITORS | THE UNIVERSITY OF CHICAGO (US) | 2015-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150306069-A1 | METHODS AND COMPOSITIONS INVOLVING RAD51 INHIBITORS | RAD51, MRE11, RAD50 | L3MBTL1 1927/4885MAPT 2482/4885ALDH1A1 3973/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.