Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.63 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.61 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2925120 | 0.86 | TRPV1 (0.70) | TRPV1ALDH1A1GAATSHRNFKB1 | |
| SCHEMBL2849365 | 0.86 | PTPN7 (0.69) | TRPV1PTPN7DUSP3 | |
| SCHEMBL30884017 | 0.86 | PTPN7 (0.69) | TRPV1PTPN7DUSP3 | |
| SCHEMBL11069853 | 0.85 | GAA (0.67) | TRPV1ALDH1A1PTPN7DUSP3GAA | |
| SCHEMBL297477 | 0.85 | ALDH1A1 (0.64) | TRPV1ALDH1A1GAATSHRNFKB1 | |
| SCHEMBL5681720 | 0.84 | ERCC1 (0.69) | TRPV1PTPN7DUSP3 | |
| SCHEMBL6380001 | 0.84 | TRPV1 (0.63) | TRPV1ALDH1A1PTPN7DUSP3GAA | |
| SCHEMBL5707095 | 0.82 | MTNR1A (0.69) | TRPV1ALDH1A1GAATSHRNFKB1 | |
| SCHEMBL6568606 | 0.82 | ALDH1A1 (0.60) | TRPV1ALDH1A1TSHRCYP1A2CYP3A4 | |
| SCHEMBL6480802 | 0.81 | NPC1 (0.60) | TRPV1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100129515-A1 | FLAVOUR MODULATING SUBSTANCES | QUEST INTERNATIONAL SERVICES B.V. (NL) | 2010-05-27 | — | — | US | claimed |
| US-20100129515-A1 | FLAVOUR MODULATING SUBSTANCES | QUEST INTERNATIONAL SERVICES B.V. (NL) | 2010-05-27 | — | — | US | disclosed |
| US-20100129515-A1 | FLAVOUR MODULATING SUBSTANCES | QUEST INTERNATIONAL SERVICES B.V. (NL) | 2010-05-27 | — | — | US | disclosed |
| EP-1915063-A2 | N-VANILLYL UREA DERIVATIVES AS FLAVOUR MODULATING SUBSTANCES | Quest International Services B.V. (NL) | 2008-04-30 | — | — | EP | disclosed |
| WO-2007013811-A2 | N-VANILLYL UREA DERIVATIVES AS FLAVOUR MODULATING SUBSTANCES | QUEST INTERNATIONAL SERVICES B.V. (NL) | 2007-02-01 | — | — | WO | disclosed |